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The β-sheet is a common motif of regular secondary structure in proteins. Beta sheets consist of beta strands connected laterally by at least two or three backbone hydrogen bonds, forming a generally twisted, pleated sheet. A β-strand is a stretch of polypeptide chain typically 3 to 10 amino acids long with backbone in an extended conformation. The supramolecular association of β-sheets has been implicated in formation of the protein aggregates and fibrils observed in many human diseases, notably the amyloidoses such as Alzheimer's disease.
Deoxyribonucleic acid is a molecule composed of two polynucleotide chains that coil around each other to form a double helix carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid (RNA) are nucleic acids. Alongside proteins, lipids and complex carbohydrates (polysaccharides), nucleic acids are one of the four major types of macromolecules that are essential for all known forms of life.
A DNA virus is a virus that has a genome made of deoxyribonucleic acid (DNA) that is replicated by a DNA polymerase. They can be divided between those that have two strands of DNA in their genome, called double-stranded DNA (dsDNA) viruses, and those that have one strand of DNA in their genome, called single-stranded DNA (ssDNA) viruses. dsDNA viruses primarily belong to two realms: Duplodnaviria and Varidnaviria, and ssDNA viruses are almost exclusively assigned to the realm Monodnaviria, which also includes dsDNA viruses. Additionally, many DNA viruses are unassigned to higher taxa. Viruses that have a DNA genome that is replicated through an RNA intermediate by a reverse transcriptase are separately considered reverse transcribing viruses and are assigned to the kingdom Pararnavirae in the realm Riboviria.
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication occurs in all living organisms acting as the most essential part for biological inheritance. This is essential for cell division during growth and repair of damaged tissues, while it also ensures that each of the new cells receives its own copy of the DNA. The cell possesses the distinctive property of division, which makes replication of DNA essential.
A wire is a single usually cylindrical, flexible strand or rod of metal. Wires are used to bear mechanical loads or electricity and telecommunications signals. Wire is commonly formed by drawing the metal through a hole in a die or draw plate. Wire gauges come in various standard sizes, as expressed in terms of a gauge number. The term 'wire' is also used more loosely to refer to a bundle of such strands, as in "multistranded wire", which is more correctly termed a wire rope in mechanics, or a cable in electricity.
Transcription is the first of several steps of DNA based gene expression in which a particular segment of DNA is copied into RNA by the enzyme RNA polymerase.
The Strand Bookstore is an independent bookstore located at 828 Broadway, at the corner of East 12th Street in the East Village neighborhood of Manhattan, New York City, two blocks south of Union Square. In addition to the main location, there is another store on the Upper West Side on Columbus Ave between West 81st and 82nd Streets, as well as kiosks in Central Park and Times Square. The company's slogan is "18 Miles Of Books," as featured on its stickers, T-shirts, and other merchandise. In 2016, The New York Times called The Strand "the undisputed king of the city’s independent bookstores."
Strand is a major thoroughfare in the City of Westminster, Central London. It runs just over 3⁄4 mile (1,200 m) from Trafalgar Square eastwards to Temple Bar, where the road becomes Fleet Street inside the City of London, and is part of the A4, a main road running west from inner London.
Cetacean stranding, commonly known as beaching, is a phenomenon in which whales and dolphins strand themselves on land, usually on a beach. Beached whales often die due to dehydration, collapsing under their own weight, or drowning when high tide covers the blowhole. Cetacean stranding has occurred since before recorded history.
The Strand Magazine was a monthly magazine founded by George Newnes, composed of short fiction and general interest articles. It was published in the United Kingdom from January 1891 to March 1950, running to 711 issues, though the first issue was on sale well before Christmas 1890. Its immediate popularity is evidenced by an initial sale of nearly 300,000. Sales increased in the early months, before settling down to a circulation of almost 500,000 copies a month, which lasted well into the 1930s. It was edited by Herbert Greenhough Smith from 1891 to 1930. The magazine's original offices were on Burleigh Street off The Strand, London. It was revived in 1998 as a quarterly magazine.
Strand is a seaside resort town in the Western Cape, South Africa. It forms part of the Helderberg region of the City of Cape Town Metropolitan Municipality, situated on the north-eastern edge of False Bay and near the foot of the Hottentots Holland Mountains. Its geographical position is between Somerset West and Gordon's Bay, and is about 50 km southeast of Cape Town City Bowl. Strand is in the Western Cape province of South Africa, and has a population of approximately 50,000. Strand's main attraction is the beach; 5 km of white sandy beach off False Bay.
Embrik Strand was an entomologist and arachnologist who classified many insect and spider species including the greenbottle blue tarantula.
Baltimore classification is a system used to classify viruses based on their manner of messenger RNA (mRNA) synthesis. By organizing viruses based on their manner of mRNA production, it is possible to study viruses that behave similarly as a distinct group. Seven Baltimore groups are described that take into consideration whether the viral genome is made of deoxyribonucleic acid (DNA) or ribonucleic acid (RNA), whether the genome is single- or double-stranded, and whether the sense of a single-stranded RNA genome is positive or negative.
Strand Lighting is an international theatre and television lighting company founded in 1914 in London's West End that supplies lighting fixtures and controls for the entertainment industry. Strand's products have been used on countless theatre productions and TV shows worldwide.
In molecular biology and genetics, the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA, refers to the nature of the roles of the strand and its complement in specifying a sequence of amino acids. Depending on the context, sense may have slightly different meanings. For example, DNA is positive-sense if an RNA version of the same sequence is translated or translatable into protein, negative-sense if not.
Silver Strand, or simply The Strand, is a low, narrow, sandy isthmus or tombolo 7 miles (11 km) long in San Diego County, California partially within the Silver Strand State Beach. It connects Coronado Island with Imperial Beach. Together with the Point Loma peninsula it shelters and defines San Diego Bay. State Route 75 (SR 75) runs the length of the strand and is a popular site for jogging and bicycling. The Silver Strand Half Marathon is run along the route each November.
Morro Strand State Beach is a protected beach within California's state park system located in north Morro Bay along California State Route 1. Morro Strand is a popular coastal frontage park on Estero Bay featuring the Morro Strand Trail and picnic sites. A three-mile stretch of beach connects the southern and northern entrances to the beach. Dogs are prohibited in part due to the nesting and protection of the Western Snowy Plover. Fishing, surfing, beach walking, and jogging are popular activities.
Oedaleosia nigricosta is a moth of the subfamily Arctiinae. It was described by George Hampson in 1900. It is found in Sierra Leone and the Gambia.
Death Stranding is an action game developed by Kojima Productions. It is the first game from director Hideo Kojima and Kojima Productions after their split from Konami in 2015. It was released by Sony Interactive Entertainment for the PlayStation 4 in November 2019 and by 505 Games for Windows in July 2020.
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