PARP16

Last updated
PARP16
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PARP16 , ARTD15, C15orf30, pART15, poly(ADP-ribose) polymerase family member 16
External IDs MGI: 2446133 HomoloGene: 9878 GeneCards: PARP16
Gene location (Human)
Ideogram human chromosome 15.svg
Chr. Chromosome 15 (human) [1]
Human chromosome 15 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 15q22.31Start65,234,460 bp [1]
End65,300,618 bp [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_017851
NM_001316943
NM_001316944

NM_177460

RefSeq (protein)

NP_001303872
NP_001303873
NP_060321

NP_803411

Location (UCSC) Chr 15: 65.23 – 65.3 Mb Chr 9: 65.2 – 65.24 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Poly (ADP-ribose) polymerase family, member 16 is a protein in humans that is encoded by the PARP16 gene. [5]

Protein Biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

Gene Basic physical and functional unit of heredity

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

Contents

Related Research Articles

Poly (ADP-ribose) polymerase InterPro Family

Poly (ADP-ribose) polymerase (PARP) is a family of proteins involved in a number of cellular processes such as DNA repair, genomic stability, and programmed cell death.

ETS1 protein-coding gene in the species Homo sapiens

Protein C-ets-1 is a protein that in humans is encoded by the ETS1 gene. The protein encoded by this gene belongs to the ETS family of transcription factors.

PARP1 protein-coding gene in the species Homo sapiens

Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. It is one of the PARP family of enzymes.

TNKS protein-coding gene in the species Homo sapiens

Tankyrase-1 is an enzyme that in humans is encoded by the TNKS gene.

PARP4 protein-coding gene in the species Homo sapiens

Poly [ADP-ribose] polymerase 4 is an enzyme that in humans is encoded by the PARP4 gene.

PARP3 protein-coding gene in the species Homo sapiens

Poly [ADP-ribose] polymerase 3 is an enzyme that in humans is encoded by the PARP3 gene.

TNKS2 protein-coding gene in the species Homo sapiens

Tankyrase-2 is an enzyme that in humans is encoded by the TNKS2 gene.

PARP2 protein-coding gene in the species Homo sapiens

Poly [ADP-ribose] polymerase 2 is an enzyme that in humans is encoded by the PARP2 gene. It is one of the PARP family of enzymes.

ADPRHL2 protein-coding gene in the species Homo sapiens

Poly(ADP-ribose) glycohydrolase ARH3 is an enzyme that in humans is encoded by the ADPRHL2 gene.

PARP8 protein-coding gene in the species Homo sapiens

Poly [ADP-ribose] polymerase 8 is an enzyme that in humans is encoded by the PARP8 gene.

TIPARP protein-coding gene in the species Homo sapiens

TCDD-inducible poly [ADP-ribose] polymerase is an enzyme that in humans is encoded by the TIPARP gene.

PARP12 protein-coding gene in the species Homo sapiens

Poly [ADP-ribose] polymerase 12 is an enzyme that in humans is encoded by the PARP12 gene.

PARP10 protein-coding gene in the species Homo sapiens

Poly [ADP-ribose] polymerase 10 is an enzyme that in humans is encoded by the PARP10 gene.

PARG protein-coding gene in the species Homo sapiens

Poly (ADP-ribose) glycohydrolase is an enzyme that in humans is encoded by the PARG gene.

DNA polymerase alpha subunit 2 protein-coding gene in the species Homo sapiens

DNA polymerase alpha subunit 2 is an enzyme that in humans is encoded by the POLA2 gene.

DNA polymerase alpha catalytic subunit protein-coding gene in the species Homo sapiens

DNA polymerase alpha catalytic subunit is an enzyme that in humans is encoded by the POLA1 gene.

Poly(adp-ribose) polymerase family member 14 protein-coding gene in the species Homo sapiens

Poly(ADP-ribose) polymerase family member 14 is a protein that, in humans, is encoded by the PARP14 gene.

HEPACAM2 protein-coding gene in the species Homo sapiens

HEPACAM family member 2 is a protein that in humans is encoded by the HEPACAM2 gene.

Adp-ribosyltransferase 5 protein-coding gene in the species Homo sapiens

ADP-ribosyltransferase 5 is a protein that in humans is encoded by the ART5 gene.

ADPRHL1 protein-coding gene in the species Homo sapiens

ADP-ribosylhydrolase like 1 is a protein that in humans is encoded by the ADPRHL1 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000138617 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032392 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. "Entrez Gene: Poly (ADP-ribose) polymerase family, member 16" . Retrieved 2013-04-03.


Further reading