PARVG

PARVG
Identifiers
Aliases	PARVG , parvin gamma
External IDs	OMIM: 608122 MGI: 2158329 HomoloGene: 11151 GeneCards: PARVG
Gene location (Human)
Chr.	Chromosome 22 (human)
End	44,219,533 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	84,227,179 bp
RNA expression pattern
	Top expressed in
	monocyte; ; spleen; ; blood; ; appendix; ; lymph node; ; bone marrow; ; bone marrow cells; ; upper lobe of left lung; ; right lung; ; oocyte;
	Top expressed in
	thymus; ; spleen; ; bone marrow; ; spermatid; ; blood; ; superior frontal gyrus; ; seminiferous tubule; ; spermatocyte; ; mucosa of small intestine; ; subcutaneous adipose tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	actin binding ; protein binding ;
Cellular component	cytoplasm ; cell junction ; plasma membrane ; cytoskeleton ; membrane ; focal adhesion ; actin cytoskeleton ;
Biological process	actin cytoskeleton reorganization ; cell-matrix adhesion ; cell adhesion ; establishment or maintenance of cell polarity ; cell projection assembly ; substrate adhesion-dependent cell spreading ;
	Sources:Amigo / QuickGO
Orthologs
	64098
	64099
	ENSG00000138964
	ENSMUSG00000022439
	Q9HBI0
	Q9ERD8
NM_001137605 ; NM_001137606 ; NM_001254741 ; NM_001254742 ; NM_001254743 ;
	NM_022141
	NM_001162500 ; NM_022321
	NP_001131077 ; NP_071424
	NP_001155972 ; NP_071716
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated February 27, 2024

Gamma-parvin is a protein that in humans is encoded by the PARVG gene.^[5]^[6]

Members of the parvin family, including PARVG, PARVA and PARVB, are actin-binding proteins associated with focal contacts.[supplied by OMIM]^[6]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000138964 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022439 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci. 114 (Pt 3): 525–38. doi:10.1242/jcs.114.3.525. PMID 11171322.
1 2 "Entrez Gene: PARVG parvin, gamma".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22" (PDF). Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi: 10.1038/990031 . PMID 10591208.
Korenbaum E, Olski TM, Noegel AA (2002). "Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans". Gene. 279 (1): 69–79. doi:10.1016/S0378-1119(01)00743-0. PMID 11722847.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954 . PMID 12529303.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi: 10.1186/gb-2004-5-10-r84 . PMC 545604 . PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Alonso ME, Bello MJ, de Campos JM, et al. (2005). "No evidence of INI1hSNF5 (SMARCB1) and PARVG point mutations in oligodendroglial neoplasms". Cancer Genet. Cytogenet. 160 (2): 169–73. doi:10.1016/j.cancergencyto.2004.12.020. PMID 15993274.
Yoshimi R, Yamaji S, Suzuki A, et al. (2006). "The gamma-parvin-integrin-linked kinase complex is critically involved in leukocyte-substrate interaction". J. Immunol. 176 (6): 3611–24. doi: 10.4049/jimmunol.176.6.3611 . PMID 16517730.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000138964 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022439 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11171322-5] Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci. 114 (Pt 3): 525–38. doi:10.1242/jcs.114.3.525. PMID 11171322.

[entrez-6] 1 2 "Entrez Gene: PARVG parvin, gamma".

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PARVG

Related Research Articles

References

Further reading