PCNX

PCNX1
Identifiers
Aliases	PCNX1 , PCNXL1, pecanex, PCNX, pecanex homolog 1 (Drosophila), pecanex homolog 1, pecanex 1
External IDs	OMIM: 617655; MGI: 1891924; HomoloGene: 40997; GeneCards: PCNX1; OMA:PCNX1 - orthologs
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q24.2 Start 70,907,405 bp [1] End 71,115,382 bp [1]
Gene location (Mouse) Chr. Chromosome 12 (mouse) [2] Band 12|12 D1 Start 81,906,797 bp [2] End 82,047,698 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in epithelium of colon Brodmann area 23 sural nerve middle temporal gyrus Achilles tendon ventricular zone parietal pleura blood Skeletal muscle tissue of rectus abdominis visceral pleura Top expressed in dentate gyrus of hippocampal formation granule cell Epithelium of choroid plexus epithelium of lens retinal pigment epithelium spermatocyte spermatid neural layer of retina temporal muscle granulocyte sternocleidomastoid muscle More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 22990 54604 Ensembl ENSG00000100731 ENSMUSG00000021140 UniProt Q96RV3 Q9QYC1 RefSeq (mRNA) NM_001308160 NM_014982 NM_018814 RefSeq (protein) NP_001295089 NP_055797 NP_061284 Location (UCSC) Chr 14: 70.91 – 71.12 Mb Chr 12: 81.91 – 82.05 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Pecanex-like protein 1 is a protein that in humans is encoded by the PCNX gene. ^{[5] [6] [7]} The gene is found in Homo sapiens , and functions as a competitive endogenous RNA of S-phase kinase associated protein 2 in lung cancer. ^{[8] [9]}

References

1. GRCh38: Ensembl release 89: ENSG00000100731 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021140 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Roux AF, Rommens JM, Read L, Duncan AM, Cox DW (July 1997). "Physical and transcription map in the region 14q24.3: identification of six novel transcripts". Genomics. 43 (2): 130–40. doi:10.1006/geno.1997.4786. PMID   9244429.
6. Geisinger A, Alsheimer M, Baier A, Benavente R, Wettstein R (April 2005). "The mammalian gene pecanex 1 is differentially expressed during spermatogenesis". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1728 (1–2): 34–43. doi:10.1016/j.bbaexp.2005.01.010. PMID   15777640.
7. "Entrez Gene: PCNX pecanex homolog (Drosophila)".
8. "PCNX1 pecanex 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2018-10-18.
9. Li J, Tian H, Pan J, Jiang N, Yang J, Zhou C, Xu D, Meng X, Gong Z (October 2017). "Pecanex functions as a competitive endogenous RNA of S-phase kinase associated protein 2 in lung cancer". Cancer Letters. 406: 36–46. doi:10.1016/j.canlet.2017.07.030. PMID   28789966.

Further reading

• Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research. 9 (3): 99–106. CiteSeerX   10.1.1.500.923 . doi:10.1093/dnares/9.3.99. PMID   12168954.
• Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. CiteSeerX   10.1.1.529.4378 . doi: 10.1093/dnares/5.5.277 . PMID   9872452.
• Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (February 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 6 (1): 63–70. doi: 10.1093/dnares/6.1.63 . PMID   10231032.