PDF (gene)

Last updated
PDF
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PDF , peptide deformylase (mitochondrial), peptide deformylase, mitochondrial
External IDs MGI: 1915273; HomoloGene: 69354; GeneCards: PDF; OMA:PDF - orthologs
Orthologs
SpeciesHumanMouse
Entrez

64146

68023

Ensembl

ENSG00000258429

ENSMUSG00000078931

UniProt

Q9HBH1

S4R2K0

RefSeq (mRNA)

NM_022341

NM_026513

RefSeq (protein)

NP_071736

NP_080789

Location (UCSC) Chr 16: 69.33 – 69.33 Mb Chr 8: 107.77 – 107.78 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Peptide deformylase, mitochondrial is an enzyme that in humans is encoded by the PDF gene. [5] [6] [7]

Contents

Related Research Articles

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Elongation factor Tu, mitochondrial is a protein that in humans is encoded by the TUFM gene. It is an EF-Tu homolog.

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Olfactory receptor 10H3 is a protein that in humans is encoded by the OR10H3 gene.

<span class="mw-page-title-main">Mitochondrial ribosomal protein L28</span> Protein-coding gene in the species Homo sapiens

39S ribosomal protein L28, mitochondrial is a protein that in humans is encoded by the MRPL28 gene.

<span class="mw-page-title-main">METAP1</span> Protein-coding gene in the species Homo sapiens

Methionine aminopeptidase 1 is an enzyme that in humans is encoded by the METAP1 gene.

<span class="mw-page-title-main">TIMM10</span> Protein-coding gene in the species Homo sapiens

Mitochondrial import inner membrane translocase subunit Tim10 is an enzyme that in humans is encoded by the TIMM10 gene.

<span class="mw-page-title-main">SOX8</span> Protein-coding gene in the species Homo sapiens

Transcription factor SOX-8 is a protein that in humans is encoded by the SOX8 gene.

<span class="mw-page-title-main">TFB2M</span> Protein-coding gene in the species Homo sapiens

Dimethyladenosine transferase 2; transcription factor B2, mitochondrial is an enzyme that in humans is encoded by the TFB2M gene.

<span class="mw-page-title-main">GFM1</span> Protein-coding gene in the species Homo sapiens

Elongation factor G 1, mitochondrial is a protein that in humans is encoded by the GFM1 gene. It is an EF-G homolog.

<span class="mw-page-title-main">PMPCA</span> Protein-coding gene in humans

Mitochondrial-processing peptidase subunit alpha is an enzyme that in humans is encoded by the PMPCA gene. This gene PMPCA encoded a protein that is a member of the peptidase M16 family. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.

<span class="mw-page-title-main">MARC2</span> Protein-coding gene in the species Homo sapiens

MOSC domain-containing protein 2, mitochondrial is a protein that in humans is encoded by the MOSC2 gene.

<span class="mw-page-title-main">Mitochondrial ribosomal protein L41</span> Protein-coding gene in the species Homo sapiens

39S ribosomal protein L41, mitochondrial is a protein that in humans is encoded by the MRPL41 gene.

<span class="mw-page-title-main">TIMM10B</span> Protein-coding gene in the species Homo sapiens

Mitochondrial import inner membrane translocase subunit Tim9 B is an enzyme that in humans is encoded by the FXC1 gene.

<span class="mw-page-title-main">MRPS26</span> Protein-coding gene in the species Homo sapiens

28S ribosomal protein S26, mitochondrial is a protein that in humans is encoded by the MRPS26 gene.

<span class="mw-page-title-main">Mitochondrial ribosomal protein L40</span> Protein-coding gene in the species Homo sapiens

39S ribosomal protein L40, mitochondrial is a protein that in humans is encoded by the MRPL40 gene.

<span class="mw-page-title-main">TSFM</span> Protein-coding gene in the species Homo sapiens

Elongation factor Ts, mitochondrial is a protein that in humans is encoded by the TSFM gene. It is an EF-Ts homolog.

<span class="mw-page-title-main">TIMM9</span> Protein-coding gene in the species Homo sapiens

Mitochondrial import inner membrane translocase subunit Tim9 is an enzyme that in humans is encoded by the TIMM9 gene.

<span class="mw-page-title-main">SARS2</span> Protein-coding gene in the species Homo sapiens

Seryl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the SARS2 gene.

<span class="mw-page-title-main">MRPS35</span> Protein-coding gene in the species Homo sapiens

28S ribosomal protein S35, mitochondrial is a protein that in humans is encoded by the MRPS35 gene.

<span class="mw-page-title-main">MRPS25</span> Protein-coding gene in the species Homo sapiens

28S ribosomal protein S25, mitochondrial is a protein that in humans is encoded by the MRPS25 gene.

<span class="mw-page-title-main">Mitochondrial translational release factor 1</span> Protein-coding gene in the species Homo sapiens

Mitochondrial translational release factor 1, also known as MTRF1 is a human gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000258429 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000078931 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Giglione C, Serero A, Pierre M, Boisson B, Meinnel T (Nov 2000). "Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms". EMBO J. 19 (21): 5916–29. doi:10.1093/emboj/19.21.5916. PMC   305796 . PMID   11060042.
  6. ↑ Lee MD, She Y, Soskis MJ, Borella CP, Gardner JR, Hayes PA, Dy BM, Heaney ML, Philips MR, Bornmann WG, Sirotnak FM, Scheinberg DA (Oct 2004). "Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics". J Clin Invest. 114 (8): 1107–16. doi:10.1172/JCI22269. PMC   522256 . PMID   15489958.
  7. ↑ "Entrez Gene: PDF peptide deformylase (mitochondrial)".

Further reading


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