PEX11A

PEX11A
Identifiers
Aliases	PEX11A , PEX11-ALPHA, PMP28, hsPEX11p, peroxisomal biogenesis factor 11 alpha, PEX11alpha
External IDs	OMIM: 603866; MGI: 1338788; HomoloGene: 20829; GeneCards: PEX11A; OMA:PEX11A - orthologs
Gene location (Human) Chr. Chromosome 15 (human) [1] Band 15q26.1 Start 89,677,764 bp [1] End 89,690,783 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 D2 Start 79,385,705 bp [2] End 79,392,879 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in jejunal mucosa germinal epithelium mucosa of transverse colon parotid gland adipose tissue lactiferous gland right lobe of liver mucosa of sigmoid colon palpebral conjunctiva subcutaneous adipose tissue Top expressed in salivary gland lacrimal gland brown adipose tissue parotid gland left lobe of liver right kidney submandibular gland zygote Paneth cell proximal tubule More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding protein homodimerization activity Cellular component integral component of membrane peroxisomal membrane peroxisome membrane integral component of peroxisomal membrane protein-containing complex Biological process regulation of peroxisome size peroxisome membrane biogenesis peroxisome organization signal transduction peroxisome fission brown fat cell differentiation regulation of lipid metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8800 18631 Ensembl ENSG00000166821 ENSMUSG00000030545 UniProt O75192 Q9Z211 RefSeq (mRNA) NM_003847 NM_001271572 NM_001271573 NM_011068 RefSeq (protein) NP_001258501 NP_001258502 NP_003838 NP_035198 Location (UCSC) Chr 15: 89.68 – 89.69 Mb Chr 7: 79.39 – 79.39 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Peroxisomal membrane protein 11A is a protein that in humans is encoded by the PEX11A gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000166821 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030545 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Schrader M, Reuber BE, Morrell JC, Jimenez-Sanchez G, Obie C, Stroh TA, Valle D, Schroer TA, Gould SJ (Dec 1998). "Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli". J Biol Chem. 273 (45): 29607–14. doi: 10.1074/jbc.273.45.29607 . PMID   9792670.
6. "Entrez Gene: PEX11A peroxisomal biogenesis factor 11A".

Further reading

• Abe I, Okumoto K, Tamura S, Fujiki Y (1998). "Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11". FEBS Lett. 431 (3): 468–72. Bibcode:1998FEBSL.431..468A. doi: 10.1016/S0014-5793(98)00815-1 . PMID   9714566.
• South ST, Gould SJ (1999). "Peroxisome Synthesis in the Absence of Preexisting Peroxisomes". J. Cell Biol. 144 (2): 255–66. doi:10.1083/jcb.144.2.255. PMC   2132891 . PMID   9922452.
• Sacksteder KA, Jones JM, South ST, et al. (2000). "Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis". J. Cell Biol. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC   2174547 . PMID   10704444.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Shimizu M, Akter MH, Emi Y, et al. (2007). "Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair". J. Biochem. 139 (3): 563–73. doi: 10.1093/jb/mvj053 . PMID   16567422.
• Orth T, Reumann S, Zhang X, et al. (2007). "The PEROXIN11 Protein Family Controls Peroxisome Proliferation in Arabidopsis". Plant Cell. 19 (1): 333–50. Bibcode:2007PlanC..19..333O. doi:10.1105/tpc.106.045831. PMC   1820951 . PMID   17220199.