PKD1L1

PKD1L1
Identifiers
Aliases	PKD1L1 , PRO19563, polycystin 1 like 1, transient receptor potential channel interacting, HTX8
External IDs	OMIM: 609721 MGI: 2156538 HomoloGene: 51376 GeneCards: PKD1L1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	47,948,466 bp
RNA expression pattern
	Top expressed in
	left ventricle; ; gastrocnemius muscle; ; subcutaneous adipose tissue; ; lymph node; ; nucleus accumbens; ; upper lobe of left lung; ; right coronary artery; ; Achilles tendon; ; hypothalamus; ; gallbladder;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ; calcium channel activity ;
Cellular component	integral component of membrane ; plasma membrane ; cell projection ; cilium ; calcium channel complex ; membrane ; ciliary membrane ; non-motile cilium ;
Biological process	ion transport ; detection of nodal flow ; detection of mechanical stimulus ; calcium ion transmembrane transport ; left/right axis specification ; calcium ion transport ; cell-cell adhesion ;
	Sources:Amigo / QuickGO
Orthologs
	168507
	171395
	ENSG00000158683
	n/a
	Q8TDX9
	n/a
	NM_138295
	XM_036157131
	NP_612152
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Polycystin 1 like 1, transient receptor potential channel interacting is a protein that in humans is encoded by the PKD1L1 gene. ^[4]

Function

This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008].

Related Research Articles

Mucolipin-1 also known as TRPML1 is a protein that in humans is encoded by the MCOLN1 gene. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.

Polycystin 1 is a protein that in humans is encoded by the PKD1 gene. Mutations of PKD1 are associated with most cases of autosomal dominant polycystic kidney disease, a severe hereditary disorder of the kidneys characterised by the development of renal cysts and severe kidney dysfunction.

TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia.

The short transient receptor potential channel 4 (TrpC4), also known as Trp-related protein 4, is a protein that in humans is encoded by the TRPC4 gene.

Short transient receptor potential channel 5 (TrpC5) also known as transient receptor protein 5 (TRP-5) is a protein that in humans is encoded by the TRPC5 gene. TrpC5 is subtype of the TRPC family of mammalian transient receptor potential ion channels.

Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name.

Transient receptor potential cation channel, subfamily M, member 7, also known as TRPM7, is a human gene encoding a protein of the same name.

<span class="mw-page-title-main">Polycystin 2</span> Protein and coding gene in humans

Polycystin-2 is a protein that in humans is encoded by the PKD2 gene.

Olfactory receptor 52N1 is a protein that in humans is encoded by the OR52N1 gene.

Olfactory receptor 4A16 is a protein that in humans is encoded by the OR4A16 gene.

Olfactory receptor 52R1 is a protein that in humans is encoded by the OR52R1 gene.

Olfactory receptor 4L1 is a protein that in humans is encoded by the OR4L1 gene.

Olfactory receptor 5AS1 is a protein that in humans is encoded by the OR5AS1 gene.

Olfactory receptor 8H1 is a protein that in humans is encoded by the OR8H1 gene.

Olfactory receptor 11L1 is a protein that in humans is encoded by the OR11L1 gene.

Olfactory receptor 4M1 is a protein that in humans is encoded by the OR4M1 gene.

Polycystic kidney disease 2-like 1 protein also known as transient receptor potential polycystic 2 is a protein that in humans is encoded by the PKD2L1 gene.

Mucolipin-2 also known as TRPML2 is a protein that in humans is encoded by the MCOLN2 gene. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.

Polycystic kidney disease 2-like 2 protein (PKD2L2) also known as transient receptor potential polycystic 5 (TRPP5) is a protein that in humans is encoded by the PKD2L2 gene.

Spectrin, beta, non-erythrocytic 5 also known as SPTBN5 is a protein that in humans is encoded by the SPTBN5 gene. SPTBN5 belongs to the spectrin family of cytoskeletal proteins.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000158683 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Polycystin 1 like 1, transient receptor potential channel interacting" . Retrieved 2017-10-16.

PKD1L1

Contents

Function

Related Research Articles

References

Further reading