PLXDC1

PLXDC1
Identifiers
Aliases	PLXDC1 , TEM3, TEM7, plexin domain containing 1
External IDs	OMIM: 606826; MGI: 1919574; HomoloGene: 10700; GeneCards: PLXDC1; OMA:PLXDC1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q12 Start 39,063,313 bp [1] End 39,154,394 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 D Start 97,814,064 bp [2] End 97,877,270 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart tendon of biceps brachii right ovary gallbladder left uterine tube left ovary body of uterus right uterine tube tibial nerve gastric mucosa Top expressed in motor neuron facial motor nucleus lateral geniculate nucleus medial geniculate nucleus lobe of cerebellum medial dorsal nucleus seminiferous tubule cerebellar vermis lumbar subsegment of spinal cord spermatid More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm integral component of membrane extracellular region cell junction soma receptor complex plasma membrane dendrite intracellular anatomical structure membrane bicellular tight junction extracellular space Biological process angiogenesis spinal cord development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57125 72324 Ensembl ENSG00000161381 ENSMUSG00000017417 UniProt Q8IUK5 Q91ZV7 RefSeq (mRNA) NM_020405 NM_001163608 NM_028199 RefSeq (protein) NP_065138 NP_001157080 NP_082475 Location (UCSC) Chr 17: 39.06 – 39.15 Mb Chr 11: 97.81 – 97.88 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Plexin domain-containing protein 1 is a protein that in humans is encoded by the PLXDC1 gene. ^{[5] [6] [7]}

See also

• Plexin
• PLXDC2
• Protein domain

References

1. GRCh38: Ensembl release 89: ENSG00000161381 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000017417 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW (Aug 2000). "Genes expressed in human tumor endothelium". Science. 289 (5482): 1197–202. Bibcode:2000Sci...289.1197S. doi:10.1126/science.289.5482.1197. PMID   10947988.
6. Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B (Sep 2001). "Cell surface tumor endothelial markers are conserved in mice and humans". Cancer Res. 61 (18): 6649–55. PMID   11559528.
7. "Entrez Gene: PLXDC1 plexin domain containing 1".

Further reading

• Fuchs B, Mahlum E, Halder C, et al. (2007). "High expression of tumor endothelial marker 7 is associated with metastasis and poor survival of patients with osteogenic sarcoma". Gene. 399 (2): 137–43. doi:10.1016/j.gene.2007.05.003. PMC   2066185 . PMID   17560052.
• Nanda A, Buckhaults P, Seaman S, et al. (2005). "Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R". Cancer Res. 64 (23): 8507–11. doi: 10.1158/0008-5472.CAN-04-2716 . PMID   15574754.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.