PNISR

PNISR
Identifiers
Aliases	PNISR , C6orf111, HSPC306, SFRS18, SRrp130, bA98I9.2, PNN-interacting serine/arginine-rich protein, PNN interacting serine and arginine rich protein
External IDs	OMIM: 616653; MGI: 1913875; HomoloGene: 32802; GeneCards: PNISR; OMA:PNISR - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6q16.2 Start 99,397,629 bp [1] End 99,425,331 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 A3 Start 21,847,583 bp [2] End 21,876,475 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum sural nerve right uterine tube left ovary anterior pituitary left lobe of thyroid gland right ovary body of uterus right lobe of thyroid gland Achilles tendon Top expressed in hand lobe of cerebellum cerebellar vermis neural layer of retina genital tubercle medullary collecting duct superior colliculus tail of embryo superior cervical ganglion Rostral migratory stream More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 25957 66625 Ensembl ENSG00000132424 ENSMUSG00000028248 UniProt Q8TF01 A2AJT4 RefSeq (mRNA) NM_015491 NM_032870 NM_001322405 NM_001322406 NM_001322408 NM_001322410 NM_001322412 NM_001322413 NM_001322414 NM_001322415 NM_001322416 NM_001322417 NM_001322418 NM_001322419 NM_025669 NM_001369189 NM_001369190 NM_001369191 RefSeq (protein) NP_001309334 NP_001309335 NP_001309337 NP_001309339 NP_001309341 NP_001309342 NP_001309343 NP_001309344 NP_001309345 NP_001309346 NP_001309347 NP_001309348 NP_056306 NP_116259 NP_079945 NP_001356118 NP_001356119 NP_001356120 Location (UCSC) Chr 6: 99.4 – 99.43 Mb Chr 4: 21.85 – 21.88 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Splicing factor, arginine/serine-rich 18 is a protein that in humans is encoded by the SFRS18 gene. ^[5]

Interactions

SFRS18 has been shown to interact with Pinin. ^[6]

References

1. GRCh38: Ensembl release 89: ENSG00000132424 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028248 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: C6orf111 chromosome 6 open reading frame 111".
6. Zimowska, Grazyna; Shi Jia; Munguba Gustavo; Jackson Moira R; Alpatov Roman; Simmons Matthew N; Shi Yujiang; Sugrue Stephen P (Nov 2003). "Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells". Invest. Ophthalmol. Vis. Sci. 44 (11). United States: 4715–23. doi:10.1167/iovs.03-0240. ISSN   0146-0404. PMID   14578391.

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Zimowska G, Shi J, Munguba G, et al. (2003). "Pinin/DRS/memA interacts with SRp75, SRm300 and SRrp130 in corneal epithelial cells". Invest. Ophthalmol. Vis. Sci. 44 (11): 4715–23. doi:10.1167/iovs.03-0240. PMID   14578391.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.