PPP1R27

PPP1R27
Identifiers
Aliases	PPP1R27 , DYSFIP1, protein phosphatase 1 regulatory subunit 27
External IDs	MGI: 1915951; HomoloGene: 45933; GeneCards: PPP1R27; OMA:PPP1R27 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,835,050 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	120,441,958 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; gastrocnemius muscle; ; skeletal muscle tissue; ; pituitary gland; ; anterior pituitary; ; bone marrow; ; left testis; ; right adrenal gland; ; right adrenal cortex; ; right testis;
	Top expressed in
	soleus muscle; ; knee joint; ; temporal muscle; ; medial head of gastrocnemius muscle; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; triceps brachii muscle; ; intercostal muscle; ; sternocleidomastoid muscle; ; otolith organ;
	More reference expression data
	n/a
Orthologs
	116729
	68701
	ENSG00000182676 ; ENSG00000288186
	ENSMUSG00000025129
	Q86WC6
	Q9D119
	NM_001007533
	NM_026814
	NP_001007534
	NP_081090
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 22, 2024

Protein phosphatase 1, regulatory subunit 27 is a protein in humans that is encoded by the PPP1R27 gene. ^[5]

Related Research Articles

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform is an enzyme that in humans is encoded by the PPP2R2B gene.

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha is an enzyme that in humans is encoded by the PPP2R3A gene. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform is an enzyme that in humans is encoded by the PPP2R2C gene.

Serine/threonine-protein phosphatase 1 regulatory subunit 10 is an enzyme that in humans is encoded by the PPP1R10 gene. This gene lies within the major histocompatibility complex class I region on chromosome 6.

Protein phosphatase 1 regulatory subunit 12B is an enzyme that in humans is encoded by the PPP1R12B gene.

Protein phosphatase 1 regulatory subunit 14B is an enzyme that in humans is encoded by the PPP1R14B gene.

Protein phosphatase 1 regulatory subunit 3C also known as PTG is an enzyme that in humans is encoded by the PPP1R3C gene.

Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene. Among its related pathways are MAPK signaling pathway and GPCR pathway. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CHP1.

Serine/threonine-protein phosphatase 4 regulatory subunit 1 is an enzyme that in humans is encoded by the PPP4R1 gene.

Phosphatase and actin regulator 3 is an enzyme that in humans is encoded by the PHACTR3 gene.

Forkhead box protein K1 is a transcription factor of the forkhead box family that in humans is encoded by the FOXK1 gene.

Protein phosphatase 1 regulatory subunit 7 is an enzyme that in humans is encoded by the PPP1R7 gene.

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma is an enzyme that in humans is encoded by the PPP2R3C gene.

Protein phosphatase 1 regulatory subunit 14C is an enzyme that in humans is encoded by the PPP1R14C gene.

Protein phosphatase 1 regulatory subunit 17 is a protein that in humans is encoded by the PPP1R17 gene.

Pyruvate dehydrogenase phosphatase regulatory subunit is a protein that in humans is encoded by the PDPR gene.

Protein phosphatase 1 regulatory subunit 12C is a protein that in humans is encoded by the PPP1R12C gene.

Myotubularin related protein 12 is a protein that in humans is encoded by the MTMR12 gene.

Protein phosphatase 1 regulatory subunit 3G is a protein that is encoded by the PPP1R3G gene in humans.

PP2A subunit B isoform delta also known as serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform is a protein that in humans is encoded by the PPP2R2D gene. It is a regulatory subunit of the heterotrimeric protein phosphatase 2 enzyme.

References

1 2 3 ENSG00000288186 GRCh38: Ensembl release 89: ENSG00000182676, ENSG00000288186 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025129 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Protein phosphatase 1, regulatory subunit 27" . Retrieved 2012-11-18.

PPP1R27

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References

Further reading