PTOV1

PTOV1
Identifiers
Aliases	PTOV1 , ACID2, PTOV-1, prostate tumor overexpressed 1, extended AT-hook containing adaptor protein, PTOV1 extended AT-hook containing adaptor protein
External IDs	OMIM: 610195; MGI: 1933946; HomoloGene: 9687; GeneCards: PTOV1; OMA:PTOV1 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19q13.33 Start 49,850,735 bp [1] End 49,860,744 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7 B3|7 Start 44,512,491 bp [2] End 44,519,212 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence ventricular zone right uterine tube right hemisphere of cerebellum anterior pituitary right testis left testis right adrenal gland right adrenal cortex left adrenal cortex Top expressed in ventricular zone entorhinal cortex perirhinal cortex CA3 field choroid plexus of fourth ventricle lactiferous gland dentate gyrus of hippocampal formation granule cell primary visual cortex superior frontal gyrus molar More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 53635 84113 Ensembl ENSG00000104960 ENSMUSG00000038502 UniProt Q86YD1 Q91VU8 RefSeq (mRNA) NM_001305105 NM_001305108 NM_017432 NM_001364745 NM_001364747 NM_001364748 NM_001364749 NM_001364750 NM_001394010 NM_133949 RefSeq (protein) NP_001292034 NP_001292037 NP_059128 NP_001351674 NP_001351676 NP_001351677 NP_001351678 NP_001351679 NP_598710 Location (UCSC) Chr 19: 49.85 – 49.86 Mb Chr 7: 44.51 – 44.52 Mb PubMed search [3] [4]
Wikidata
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Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000104960 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038502 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Santamaria A, Fernandez PL, Farre X, Benedit P, Reventos J, Morote J, Paciucci R, Thomson TM (Feb 2003). "PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle". Am J Pathol. 162 (3): 897–905. doi:10.1016/S0002-9440(10)63885-0. PMC   1868092 . PMID   12598323.
6. Santamaria A, Castellanos E, Gomez V, Benedit P, Renau-Piqueras J, Morote J, Reventos J, Thomson TM, Paciucci R (Feb 2005). "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts". Mol Cell Biol. 25 (5): 1900–11. doi:10.1128/MCB.25.5.1900-1911.2005. PMC   549350 . PMID   15713644.
7. "Entrez Gene: PTOV1 prostate tumor overexpressed gene 1".

Further reading

• Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell. Proteomics. 4 (6): 785–95. doi: 10.1074/mcp.M500021-MCP200 . PMID   15778465.
• Mittler G, Stühler T, Santolin L, et al. (2004). "A novel docking site on Mediator is critical for activation by VP16 in mammalian cells". EMBO J. 22 (24): 6494–504. doi:10.1093/emboj/cdg619. PMC   291814 . PMID   14657022.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Benedit P, Paciucci R, Thomson TM, et al. (2001). "PTOV1, a novel protein overexpressed in prostate cancer containing a new class of protein homology blocks". Oncogene. 20 (12): 1455–64. doi: 10.1038/sj.onc.1204233 . PMID   11313889.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.