PTOV1

PTOV1
Identifiers
Aliases	PTOV1 , ACID2, PTOV-1, prostate tumor overexpressed 1, extended AT-hook containing adaptor protein, PTOV1 extended AT-hook containing adaptor protein
External IDs	OMIM: 610195 MGI: 1933946 HomoloGene: 9687 GeneCards: PTOV1
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,860,744 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,519,212 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; right uterine tube; ; anterior pituitary; ; Right adrenal gland; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; canal of the cervix; ; stromal cell of endometrium; ; left uterine tube; ; nucleus accumbens;
	Top expressed in
	entorhinal cortex; ; superior frontal gyrus; ; molar; ; ganglionic eminence; ; external carotid artery; ; internal carotid artery; ; maxillary prominence; ; atrium; ; lip; ; somite;
	More reference expression data
	More reference expression data
Orthologs
	53635
	84113
	ENSG00000104960
	ENSMUSG00000038502
	Q86YD1
	Q91VU8
NM_001305105 ; NM_001305108 ; NM_017432 ; NM_001364745 ; NM_001364747 ;
	NM_001364748 ; NM_001364749 ; NM_001364750 ; NM_001394010
	NM_133949
NP_001292034 ; NP_001292037 ; NP_059128 ; NP_001351674 ; NP_001351676 ;
	NP_001351677 ; NP_001351678 ; NP_001351679
	NP_598710
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated September 30, 2022

Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000104960 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038502 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Santamaria A, Fernandez PL, Farre X, Benedit P, Reventos J, Morote J, Paciucci R, Thomson TM (Feb 2003). "PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle". Am J Pathol. 162 (3): 897–905. doi:10.1016/S0002-9440(10)63885-0. PMC 1868092 . PMID 12598323.
↑ Santamaria A, Castellanos E, Gomez V, Benedit P, Renau-Piqueras J, Morote J, Reventos J, Thomson TM, Paciucci R (Feb 2005). "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts". Mol Cell Biol. 25 (5): 1900–11. doi:10.1128/MCB.25.5.1900-1911.2005. PMC 549350 . PMID 15713644.
↑ "Entrez Gene: PTOV1 prostate tumor overexpressed gene 1".

Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell. Proteomics. 4 (6): 785–95. doi: 10.1074/mcp.M500021-MCP200 . PMID 15778465.
Mittler G, Stühler T, Santolin L, et al. (2004). "A novel docking site on Mediator is critical for activation by VP16 in mammalian cells". EMBO J. 22 (24): 6494–504. doi:10.1093/emboj/cdg619. PMC 291814 . PMID 14657022.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Benedit P, Paciucci R, Thomson TM, et al. (2001). "PTOV1, a novel protein overexpressed in prostate cancer containing a new class of protein homology blocks". Oncogene. 20 (12): 1455–64. doi: 10.1038/sj.onc.1204233 . PMID 11313889.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000104960 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038502 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12598323-5] Santamaria A, Fernandez PL, Farre X, Benedit P, Reventos J, Morote J, Paciucci R, Thomson TM (Feb 2003). "PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle". Am J Pathol. 162 (3): 897–905. doi:10.1016/S0002-9440(10)63885-0. PMC 1868092 . PMID 12598323.

[pmid15713644-6] Santamaria A, Castellanos E, Gomez V, Benedit P, Renau-Piqueras J, Morote J, Reventos J, Thomson TM, Paciucci R (Feb 2005). "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts". Mol Cell Biol. 25 (5): 1900–11. doi:10.1128/MCB.25.5.1900-1911.2005. PMC 549350 . PMID 15713644.

[entrez-7] "Entrez Gene: PTOV1 prostate tumor overexpressed gene 1".

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PTOV1

Related Research Articles

References

Further reading