Her most important contribution is a model based on a Bayesian network that integrates more than 60 single-nucleotide polymorphisms (SNPs) and other biomarkers to compute the risk for stroke in patients with sickle cell anemia. This model was shown to have high sensitivity and specificity and demonstrated, for the first time, how an accurate risk prediction model of a complex genetic trait that is modulated by several interacting genes can be built using Bayesian networks.[2]
A controversial paper regarding the genetics of aging with which she was associated was retracted from the journal Science in 2011 due to flawed data.[3][4] The corrected version was published in PLOS ONE,[5] and several of the genes found associated with exceptional human longevity were replicated in other studies of centenarians.[6][7][8][9]
Publications
She has published several peer-reviewed papers. According to Scopus the most cited ones are:
This page is based on this Wikipedia article Text is available under the CC BY-SA 4.0 license; additional terms may apply. Images, videos and audio are available under their respective licenses.