Paul Georges Dieulafoy | |
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![]() Undated portrait of Dieulafoy | |
Born | Toulouse, France | 18 November 1839
Died | 26 June 1911 71) Paris, France | (aged
Education | Académie Nationale de Médecine |
Spouse | Claire Bessaignet |
Scientific career | |
Fields | Medical physician and surgeon |
Institutions | Holy Trinity Church of Paris Hôtel-Dieu de Paris University of Paris |
Paul Georges Dieulafoy (18 November 1839 – 16 August 1911) was a French physician and surgeon. He is best known for his study of acute appendicitis and his description of Dieulafoy's lesion, a rare cause of gastric bleeding.
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Dieulafoy was born in Toulouse. He studied medicine in Paris and earned his doctorate in 1869. In 1863, during his third year of medical school, Dieulafoy went to Paris to attend the clinical department of Professor Armand Trousseau. [1] The two men remained close until the former's death in 1867, with Dieulafoy being referred to as Trousseau's spiritual son. [1] Dieulafoy later led an ambulance service at the Holy Trinity Church of Paris during the Franco-Prussian war, became Chief of Medicine at the famed Hôtel-Dieu de Paris, taught pathology in the University of Paris, and was elected president of the French Academy of Medicine in 1910 after being a member since 1890.
Dieulafoy married his cousin Claire Bessaignet in 1872, however the couple remained childless their entire marriage. He died in Paris on 16 August 1911 after post-surgery complications, and was buried in Montmartre cemetery. [1]
He perfected a pump-like device for use in thoracentesis, and extensively studied pleurisy and liver conditions including hydatid disease and epidemic hepatitis. However, he is perhaps best known for his study of appendicitis. Dieulafoy described its early symptoms and clinical manifestations in detail, most notably the collection of symptoms now known as Dieulafoy's triad (more below), and was one of the first physicians to stress the importance of surgery in the treatment of this condition. He declared: "Le traitement médical de l'appendicite aiguë n'existe pas (The medical treatment of acute appendicitis does not exist)". His Handbook of Internal Pathology, published from 1880 to 1884, was widely used at the time. Between 1899 and 1910 he also published, in several volumes, the case reports from his private practice.
In 1890, Dieulafoy, André Chantemesse and Georges-Fernand Widal described a pulmonary condition found in persons who habitually fed pigeons in the streets. They termed it "mycotic pseudotuberculosis", now known as allergic bronchopulmonary aspergillosis.
Peptic ulcer disease is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. The most common symptoms of a duodenal ulcer are waking at night with upper abdominal pain, and upper abdominal pain that improves with eating. With a gastric ulcer, the pain may worsen with eating. The pain is often described as a burning or dull ache. Other symptoms include belching, vomiting, weight loss, or poor appetite. About a third of older people with peptic ulcers have no symptoms. Complications may include bleeding, perforation, and blockage of the stomach. Bleeding occurs in as many as 15% of cases.
Appendicitis is inflammation of the appendix. Symptoms commonly include right lower abdominal pain, nausea, vomiting, and decreased appetite. However, approximately 40% of people do not have these typical symptoms. Severe complications of a ruptured appendix include widespread, painful inflammation of the inner lining of the abdominal wall and sepsis.
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity of the walls of arteries; this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of arteriosclerosis caused by the buildup of fatty plaques, cholesterol, and some other substances in and on the artery walls.
Heartburn, also known as pyrosis, cardialgia or acid indigestion, is a burning sensation in the central chest or upper central abdomen. Heartburn is usually due to regurgitation of gastric acid into the esophagus. It is the major symptom of gastroesophageal reflux disease (GERD).
Upper gastrointestinal bleeding (UGIB) is gastrointestinal bleeding in the upper gastrointestinal tract, commonly defined as bleeding arising from the esophagus, stomach, or duodenum. Blood may be observed in vomit or in altered form as black stool. Depending on the amount of the blood loss, symptoms may include shock.
Coffee ground vomitus refers to a particular appearance of vomit. Within organic heme molecules of red blood cells is the element iron, which oxidizes following exposure to gastric acid. This reaction causes the vomitus to look like ground coffee.
Dieulafoy's lesion is a medical condition characterized by a large tortuous artery most commonly in the stomach wall (submucosal) that erodes and bleeds. It can present in any part of the gastrointestinal tract. It can cause gastric hemorrhage but is relatively uncommon. It is thought to cause less than 5% of all gastrointestinal bleeds in adults. It was named after French surgeon Paul Georges Dieulafoy, who described this condition in his paper "Exulceratio simplex: Leçons 1-3" in 1898. It is also called "caliber-persistent artery" or "aneurysm" of gastric vessels. However, unlike most other aneurysms, these are thought to be developmental malformations rather than degenerative changes.
A Meckel's diverticulum, a true congenital diverticulum, is a slight bulge in the small intestine present at birth and a vestigial remnant of the vitelline duct. It is the most common malformation of the gastrointestinal tract and is present in approximately 2% of the population, with males more frequently experiencing symptoms.
Gastritis is the inflammation of the lining of the stomach. It may occur as a short episode or may be of a long duration. There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain. Other possible symptoms include nausea and vomiting, bloating, loss of appetite and heartburn. Complications may include stomach bleeding, stomach ulcers, and stomach tumors. When due to autoimmune problems, low red blood cells due to not enough vitamin B12 may occur, a condition known as pernicious anemia.
Mallory–Weiss syndrome is a condition where high intra-abdominal pressures causes laceration and bleeding of the mucosa called Mallory-Weiss tears. Additionally, Mallory–Weiss syndrome is one of the most common causes of acute upper gastrointestinal bleeding, counting of around 1-15% of all cases in adults and less than 5% in children. It has been found that tears are up to 2 to 4 times more prevalent in men than women. The tears can cause upper gastrointestinal bleeding and predominantly occur where the esophagus meets the stomach. However, the tears can happen anywhere from the middle of the esophagus to the cardia of the stomach. Mallory–Weiss syndrome is often caused by constant vomiting and retching from alcoholism or bulimia. Gastroesophageal reflux disease (GERD) is another risk factor that is often linked with Mallory–Weiss syndrome. However, not every individual with Mallory–Weiss syndrome will have these risk factors. Individuals with Mallory–Weiss syndrome will have hematemesis, however the symptoms can vary.
Gastrointestinal diseases refer to diseases involving the gastrointestinal tract, namely the esophagus, stomach, small intestine, large intestine and rectum; and the accessory organs of digestion, the liver, gallbladder, and pancreas.
Jean-Nicolas Corvisart-Desmarets was a French physician.
Armand Trousseau was a French internist. His contributions to medicine include Trousseau sign of malignancy, Trousseau sign of latent tetany, Trousseau–Lallemand bodies. He is sometimes credited with the quip "use new drugs quickly, while they still work", though Michel-Philippe Bouvart had said the same over 40 years earlier.
Valentino's syndrome is pain presenting in the right lower quadrant of the abdomen caused by a duodenal ulcer with perforation through the retroperitoneum.
Dieulafoy is a surname of French origin. Notable people with the surname include:
Epiploic appendagitis (EA) is an uncommon, benign, self-limiting inflammatory process of the epiploic appendices. Other, older terms for the process include appendicitis epiploica and appendagitis, but these terms are used less now in order to avoid confusion with acute appendicitis.
A stress ulcer is a single or multiple mucosal defect usually caused by physiological stress which can become complicated by upper gastrointestinal bleeding. These ulcers can be caused by shock, sepsis, trauma or other conditions and are found in patients with chronic illnesses. These ulcers are a significant issue in patients in critical and intensive care.
Germain Sée was a French clinician who was a native of Ribeauvillé, Haut-Rhin.
A Cameron lesion is a linear erosion or ulceration of the mucosal folds lining the stomach where it is constricted by the thoracic diaphragm in persons with large hiatal hernias. The lesions may cause chronic blood loss resulting in iron deficiency anemia; less often they cause acute bleeding.
Computed tomography of the head uses a series of X-rays in a CT scan of the head taken from many different directions; the resulting data is transformed into a series of cross sections of the brain using a computer program. CT images of the head are used to investigate and diagnose brain injuries and other neurological conditions, as well as other conditions involving the skull or sinuses; it used to guide some brain surgery procedures as well. CT scans expose the person getting them to ionizing radiation which has a risk of eventually causing cancer; some people have allergic reactions to contrast agents that are used in some CT procedures.