Phospholipase A2 group IVD is a protein that in humans is encoded by the PLA2G4D gene. [5]
Phospholipase A2 group IVD is a protein that in humans is encoded by the PLA2G4D gene. [5]
The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids. [6]
The enzyme phospholipase A2 (EC 3.1.1.4, PLA2, systematic name phosphatidylcholine 2-acylhydrolase) catalyse the cleavage of fatty acids in position 2 of phospholipids, hydrolyzing the bond between the second fatty acid “tail” and the glycerol molecule:
Uteroglobin, or blastokinin, also known as secretoglobin family 1A member 1 (SCGB1A1), is a protein that in humans is encoded by the SCGB1A1 gene.
Chemokine ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils. CCL20 is implicated in the formation and function of mucosal lymphoid tissues via chemoattraction of lymphocytes and dendritic cells towards the epithelial cells surrounding these tissues. CCL20 elicits its effects on its target cells by binding and activating the chemokine receptor CCR6.
The enzyme lysophospholipase (EC 3.1.1.5) catalyzes the reaction
Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene.
85 kDa calcium-independent phospholipase A2, also known as 85/88 kDa calcium-independent phospholipase A2, Group VI phospholipase A2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, or Patatin-like phospholipase domain-containing protein 9 is an enzyme that in humans is encoded by the PLA2G6 gene.
Calcium-dependent phospholipase A2 is an enzyme that in humans is encoded by the PLA2G5 gene.
T-complex protein 1 subunit epsilon is a protein that in humans is encoded by the CCT5 gene.
Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene.
MAP kinase-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MKNK1 gene.
Cytosolic phospholipase A2 gamma is an enzyme that in humans is encoded by the PLA2G4C gene.
Group 10 secretory phospholipase A2 is an enzyme that in humans is encoded by the PLA2G10 gene.
Group IID secretory phospholipase A2 is an enzyme that in humans is encoded by the PLA2G2D gene.
MAP kinase-activated protein kinase 5 is an enzyme that in humans is encoded by the MAPKAPK5 gene. The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases, including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately-spliced transcript variants of this gene encoding distinct isoforms have been reported.
LYPLA3, also known as Group XV phospholipase A2, is an enzyme that in humans is encoded by the PLA2G15 gene.
Tyrosine-protein phosphatase non-receptor type 3 is an enzyme that in humans is encoded by the PTPN3 gene.
Calcium-independent phospholipase A2-gamma is an enzyme that in humans is encoded by the PNPLA8 gene.
Phospholipase A2, group IVB (cytosolic), also known as PLA2G4B, is a human gene.
Secretory phospholipase A2 receptor is a protein that in humans is encoded by the PLA2R1 gene.
Diacylglycerol O-acyltransferase 2 (DGAT2) is a protein that in humans is encoded by the DGAT2 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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