RAB26

RAB26
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2G6B
Identifiers
Aliases	RAB26 , V46133, member RAS oncogene family
External IDs	OMIM: 605455; MGI: 2443284; HomoloGene: 25655; GeneCards: RAB26; OMA:RAB26 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16p13.3 Start 2,140,803 bp [1] End 2,154,165 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 A3.3 Start 24,746,215 bp [2] End 24,753,184 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum cerebellar vermis right frontal lobe putamen nucleus accumbens caudate nucleus anterior cingulate cortex Brodmann area 9 parotid gland body of pancreas Top expressed in dentate gyrus of hippocampal formation granule cell superior frontal gyrus primary visual cortex otic vesicle parotid gland hippocampus proper Region I of hippocampus proper lacrimal gland temporal lobe prefrontal cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding protein binding GMP binding GTPase activity Cellular component intrinsic component of plasma membrane Golgi membrane Golgi apparatus transport vesicle membrane membrane cytoplasmic vesicle endosome plasma membrane synaptic vesicle secretory granule membrane anchored component of synaptic vesicle membrane Biological process protein transport exocrine system development regulated exocytosis Golgi to plasma membrane protein transport vesicle docking involved in exocytosis protein secretion regulation of exocytosis intracellular protein transport Rab protein signal transduction regulation of protein catabolic process at presynapse, modulating synaptic transmission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25837 328778 Ensembl ENSG00000167964 ENSMUSG00000079657 UniProt Q9ULW5 Q504M8 RefSeq (mRNA) NM_001308053 NM_014353 NM_177375 RefSeq (protein) NP_001294982 NP_055168 NP_796349 Location (UCSC) Chr 16: 2.14 – 2.15 Mb Chr 17: 24.75 – 24.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ras-related protein Rab-26 is a protein that in humans is encoded by the RAB26 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000167964 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000079657 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Seki N, Yoshikawa T, Hattori A, Miyajima N, Muramatsu M, Saito T (Oct 2000). "cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP-binding protein on chromosome 16p13.3 region". J Hum Genet. 45 (5): 309–14. doi: 10.1007/s100380070023 . PMID   11043516.
6. "Entrez Gene: RAB26 RAB26, member RAS oncogene family".

Further reading

• Swick L, Kapatos G (2006). "A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactions". J. Neurochem. 97 (5): 1447–55. doi:10.1111/j.1471-4159.2006.03836.x. PMC   2239266 . PMID   16696853.
• Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94. Bibcode:2004Natur.432..988M. doi: 10.1038/nature03187 . PMID   15616553.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi: 10.1074/jbc.M212341200 . PMID   12578829.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Yoshie S, Imai A, Nashida T, Shimomura H (2000). "Expression, characterization, and localization of Rab26, a low molecular weight GTP-binding protein, in the rat parotid gland". Histochem. Cell Biol. 113 (4): 259–63. doi:10.1007/s004180000130. PMID   10857477. S2CID   39587270.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.