RAB3IP

RAB3IP
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4LHX, 4LHY, 4LHZ, 4UJ3, 4UJ4, 4UJ5
Identifiers
Aliases	RAB3IP , RABIN3, RABIN8, RAB3A interacting protein
External IDs	OMIM: 608686 MGI: 105933 HomoloGene: 32340 GeneCards: RAB3IP
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q15 Start 69,738,860 bp [1] End 69,823,204 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10 D2|10 64.96 cM Start 116,741,689 bp [2] End 116,786,674 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans cerebellar vermis kidney body of pancreas cerebellar hemisphere rectum retinal pigment epithelium anterior pituitary bone marrow cells corpus callosum Top expressed in kidney proximal tubule seminiferous tubule spermatid retinal pigment epithelium medullary collecting duct utricle yolk sac spermatocyte lacrimal gland More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding guanyl-nucleotide exchange factor activity identical protein binding Cellular component cytoplasm ciliary basal body cytosol centrosome cell projection cytoskeleton lamellipodium nucleus Biological process protein localization to organelle protein transport Golgi to plasma membrane transport protein targeting to membrane cilium assembly ciliary basal body-plasma membrane docking Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 117177 216363 Ensembl ENSG00000127328 ENSMUSG00000064181 UniProt Q96QF0 Q68EF0 RefSeq (mRNA) NM_001024647 NM_001278402 NM_022456 NM_175623 NM_175624 NM_175625 NM_175626 NM_175627 NM_001003950 NM_001359645 RefSeq (protein) NP_001019818 NP_001265331 NP_071901 NP_783322 NP_783323 NP_783324 NP_001003950 NP_001346574 Location (UCSC) Chr 12: 69.74 – 69.82 Mb Chr 10: 116.74 – 116.79 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RAB3A-interacting protein is a protein that in humans is encoded by the RAB3IP gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000127328 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000064181 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: RAB3IP RAB3A interacting protein (rabin3)".

Further reading

• Newport J, Roemer MI (1975). "Comparative perinatal mortality under medical care foundations and other delivery models". Inquiry: A Journal of Medical Care Organization, Provision and Financing. 12 (1): 10–7. PMID   123217.
• Brondyk WH, McKiernan CJ, Fortner KA, et al. (1995). "Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A". Mol. Cell. Biol. 15 (3): 1137–43. doi:10.1128/MCB.15.3.1137. PMC   230335 . PMID   7532276.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• de Bruijn DR, dos Santos NR, Kater-Baats E, et al. (2002). "The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP". Genes Chromosomes Cancer. 34 (3): 285–98. doi:10.1002/gcc.10073. PMID   12007189. S2CID   11734893.
• Hattula K, Furuhjelm J, Arffman A, Peränen J (2003). "A Rab8-specific GDP/GTP Exchange Factor Is Involved in Actin Remodeling and Polarized Membrane Transport". Mol. Biol. Cell. 13 (9): 3268–80. doi:10.1091/mbc.E02-03-0143. PMC   124888 . PMID   12221131.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.

External links

• Overview of all the structural information available in the PDB for UniProt : Q96QF0 (Rab-3A-interacting protein) at the PDBe-KB .