RABL6

RABL6
Identifiers
Aliases	RABL6 , C9orf86, PARF, RBEL1, pp8875, RAB, member RAS oncogene family-like 6, RAB, member RAS oncogene family like 6
External IDs	OMIM: 610615; MGI: 2442633; HomoloGene: 11674; GeneCards: RABL6; OMA:RABL6 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q34.3 Start 136,807,943 bp [1] End 136,841,187 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 A3 Start 25,473,030 bp [2] End 25,498,533 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum nucleus accumbens apex of heart right frontal lobe anterior cingulate cortex gastrocnemius muscle caudate nucleus muscle of thigh pylorus amygdala Top expressed in tail of embryo interventricular septum genital tubercle superior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell muscle of thigh internal carotid artery cerebellar cortex lacrimal gland More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding GTP binding protein binding GTPase activity Cellular component cytoplasm nucleus centrosome cytosol intracellular anatomical structure Biological process small GTPase mediated signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55684 227624 Ensembl ENSG00000196642 ENSMUSG00000015087 UniProt Q3YEC7 Q5U3K5 RefSeq (mRNA) NM_024718 NM_001173988 NM_001173989 NM_017995 NM_001024616 RefSeq (protein) NP_001167459 NP_001167460 NP_078994 NP_001019787 Location (UCSC) Chr 9: 136.81 – 136.84 Mb Chr 2: 25.47 – 25.5 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Rab-like protein 6 is a protein that in humans is encoded by the RABL6 gene. ^{[5] [6] [7] [8]}

Interactions

RABL6 has been shown to interact with MDFI. ^[9]

References

1. GRCh38: Ensembl release 89: ENSG00000196642 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000015087 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Tompkins V, Hagen J, Zediak VP, Quelle DE (Mar 2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. doi: 10.4161/cc.5.6.2560 . PMID   16582619.
6. Montalbano J, Jin W, Sheikh MS, Huang Y (Dec 2007). "RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer". The Journal of Biological Chemistry. 282 (52): 37640–9. doi: 10.1074/jbc.M704760200 . PMID   17962191.
7. Montalbano J, Lui K, Sheikh MS, Huang Y (Jul 2009). "Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation". The Journal of Biological Chemistry. 284 (27): 18129–42. doi: 10.1074/jbc.M109.009597 . PMC   2709392 . PMID   19433581.
8. "Entrez Gene: C9orf86 chromosome 9 open reading frame 86".
9. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.

External links

• Human RABL6 genome location and RABL6 gene details page in the UCSC Genome Browser .

Further reading

• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Cui YP, Wang JB, Zhang XY, Bi MX, Guo LP, Lu SH (Sep 2003). "Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene". World Journal of Gastroenterology. 9 (9): 1892–6. doi: 10.3748/wjg.v9.i9.1892 . PMC   4656638 . PMID   12970870.
• Cui Y, Wang J, Zhang X, Lang R, Bi M, Guo L, Lu SH (Mar 2003). "ECRG2, a novel candidate of tumor suppressor gene in the esophageal carcinoma, interacts directly with metallothionein 2A and links to apoptosis". Biochemical and Biophysical Research Communications. 302 (4): 904–15. doi:10.1016/S0006-291X(03)00122-0. PMID   12646258.