RNF146

RNF146
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D8T, 3V3L
Identifiers
Aliases	RNF146 , dJ351K20.1, ring finger protein 146
External IDs	OMIM: 612137 MGI: 1915281 HomoloGene: 12227 GeneCards: RNF146
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6q22.33 Start 127,266,726 bp [1] End 127,288,567 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 A4 Start 29,220,172 bp [2] End 29,238,438 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar vermis cerebellar hemisphere gastric mucosa tibia biceps brachii middle temporal gyrus tendon Achilles tendon Brodmann area 23 gastrocnemius muscle Top expressed in interventricular septum motor neuron Region I of hippocampus proper cumulus cell superior cervical ganglion primitive streak trigeminal ganglion medial ganglionic eminence substantia nigra utricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding protein binding metal ion binding ubiquitin-protein transferase activity poly-ADP-D-ribose binding ubiquitin protein ligase activity transferase activity Cellular component cytoplasm cytosol nucleus nucleoplasm plasma membrane Biological process positive regulation of canonical Wnt signaling pathway protein K48-linked ubiquitination protein ubiquitination protein autoubiquitination ubiquitin-dependent protein catabolic process Wnt signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81847 68031 Ensembl ENSG00000118518 ENSMUSG00000038876 UniProt Q9NTX7 Q9CZW6 RefSeq (mRNA) NM_001242844 NM_001242845 NM_001242846 NM_001242847 NM_001242848 NM_001242849 NM_001242850 NM_001242851 NM_001242852 NM_030963 NM_001110196 NM_001110197 NM_001110198 NM_001284279 NM_026518 RefSeq (protein) NP_001229773 NP_001229774 NP_001229775 NP_001229776 NP_001229777 NP_001229778 NP_001229779 NP_001229780 NP_001229781 NP_112225 NP_001103666 NP_001103667 NP_001103668 NP_001271208 NP_080794 Location (UCSC) Chr 6: 127.27 – 127.29 Mb Chr 10: 29.22 – 29.24 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RING finger protein 146 is a protein that in humans is encoded by the RNF146 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000118518 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038876 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: RNF146 ring finger protein 146".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• von Rotz RC, Kins S, Hipfel R, et al. (2005). "The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease". Eur. J. Neurosci. 21 (5): 1289–98. doi:10.1111/j.1460-9568.2005.03977.x. PMID   15813938. S2CID   2715969.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.