RNF31

RNF31
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2CT7, 4DBG, 4JUY, 4LJO, 4LJP, 4LJQ, 4OWF, 4OYJ, 4OYK, 4P09, 4P0A, 4P0B, 5EDV
Identifiers
Aliases	RNF31 , HOIP, ZIBRA, ring finger protein 31, Paul
External IDs	OMIM: 612487 MGI: 1934704 HomoloGene: 33228 GeneCards: RNF31
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q12 Start 24,146,683 bp [1] End 24,160,660 bp [1]
Gene location (Mouse) Chr. Chromosome 14 (mouse) [2] Band 14|14 C3 Start 55,829,165 bp [2] End 55,841,150 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen blood right lobe of thyroid gland anterior pituitary body of pancreas left lobe of thyroid gland left uterine tube prostate fundus upper lobe of left lung Top expressed in internal carotid artery yolk sac duodenum jejunum thymus superior frontal gyrus external carotid artery lacrimal gland skeletal muscle tissue lip More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding ubiquitin-protein transferase activity ubiquitin binding protein binding ubiquitin protein ligase binding transferase activity Cellular component cytoplasm cytosol LUBAC complex CD40 receptor complex cytoplasmic side of plasma membrane Biological process positive regulation of protein targeting to mitochondrion CD40 signaling pathway regulation of tumor necrosis factor-mediated signaling pathway protein polyubiquitination positive regulation of NF-kappaB transcription factor activity positive regulation of I-kappaB kinase/NF-kappaB signaling I-kappaB kinase/NF-kappaB signaling T cell receptor signaling pathway protein linear polyubiquitination protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55072 268749 Ensembl ENSG00000092098 ENSG00000285152 ENSMUSG00000047098 UniProt Q96EP0 Q924T7 RefSeq (mRNA) NM_017999 NM_001310332 NM_194346 RefSeq (protein) NP_001297261 NP_060469 NP_919327 Location (UCSC) Chr 14: 24.15 – 24.16 Mb Chr 14: 55.83 – 55.84 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RING finger protein 31 is a protein that in humans is encoded by the RNF31 gene. ^{[5] [6]}

The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. ^[6]

See also

• RING finger domain

References

1. ENSG00000285152 GRCh38: Ensembl release 89: ENSG00000092098, ENSG00000285152 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047098 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. van der Reijden BA, Erpelinck-Verschueren CA, Lowenberg B, Jansen JH (Sep 1999). "TRIADs: a new class of proteins with a novel cysteine-rich signature". Protein Sci. 8 (7): 1557–61. doi:10.1110/ps.8.7.1557. PMC   2144383 . PMID   10422847.
6. "Entrez Gene: RNF31 ring finger protein 31".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Saurin AJ, Borden KL, Boddy MN, Freemont PS (1996). "Does this have a familiar RING?". Trends Biochem. Sci. 21 (6): 208–14. doi:10.1016/s0968-0004(96)80017-x. PMID   8744354.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Jikuya H, Takano J, Kikuno R, et al. (2003). "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones". DNA Res. 10 (1): 49–57. doi: 10.1093/dnares/10.1.49 . PMID   12693554.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Thompson HG, Harris JW, Lin L, Brody JP (2004). "Identification of the protein Zibra, its genomic organization, regulation, and expression in breast cancer cells". Exp. Cell Res. 295 (2): 448–59. doi:10.1016/j.yexcr.2004.01.019. PMID   15093743.
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID   15146197. S2CID   27764390.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi: 10.1016/j.cell.2006.03.032 . PMID   16713569.
• Kirisako T, Kamei K, Murata S, et al. (2006). "A ubiquitin ligase complex assembles linear polyubiquitin chains". EMBO J. 25 (20): 4877–87. doi:10.1038/sj.emboj.7601360. PMC   1618115 . PMID   17006537.

External links

• RNF31+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)