RRN3

Last updated
RRN3
Identifiers
Aliases RRN3 , A-270G1.2, TIFIA, RRN3 homolog, RNA polymerase I transcription factor
External IDs OMIM: 605121 MGI: 1925255 HomoloGene: 39531 GeneCards: RRN3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001301064
NM_018427

NM_001039521

RefSeq (protein)

NP_001287993
NP_060897

NP_001034610

Location (UCSC) Chr 16: 15.06 – 15.09 Mb Chr 16: 13.6 – 13.63 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RNA polymerase I-specific transcription initiation factor RRN3 is an enzyme that in humans is encoded by the RRN3 gene. [5] [6] [7]

Contents

Interactions

RRN3 has been shown to interact with TAF1B. [6]

Related Research Articles

<span class="mw-page-title-main">Transcription preinitiation complex</span> Complex of proteins necessary for gene transcription in eukaryotes and archaea

The preinitiation complex is a complex of approximately 100 proteins that is necessary for the transcription of protein-coding genes in eukaryotes and archaea. The preinitiation complex positions RNA polymerase II at gene transcription start sites, denatures the DNA, and positions the DNA in the RNA polymerase II active site for transcription.

RNA polymerase 1 is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA, a type of RNA that accounts for over 50% of the total RNA synthesized in a cell.

<span class="mw-page-title-main">POLR2A</span> Protein-coding gene in the species Homo sapiens

DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that in humans is encoded by the POLR2A gene.

<span class="mw-page-title-main">UBTF</span>

Nucleolar transcription factor 1 is a protein that in humans is encoded by the UBTF gene.

<span class="mw-page-title-main">TAF10</span> Protein-coding gene in the species Homo sapiens

Transcription initiation factor TFIID subunit 10 is a protein that in humans is encoded by the TAF10 gene.

<span class="mw-page-title-main">TAF15</span>

TATA-binding protein-associated factor 2N is a protein that in humans is encoded by the TAF15 gene.

<span class="mw-page-title-main">GTF2H2</span> Protein-coding gene in the species Homo sapiens

General transcription factor IIH subunit 2 is a protein that in humans is encoded by the GTF2H2 gene.

<span class="mw-page-title-main">POLR1D</span>

DNA-directed RNA polymerases I and III subunit RPAC2 is a protein that in humans is encoded by the POLR1D gene.

<span class="mw-page-title-main">POLR1C</span> Protein-coding gene in the species Homo sapiens

DNA-directed RNA polymerases I and III subunit RPAC1 is a protein that in humans is encoded by the POLR1C gene.

<span class="mw-page-title-main">POLR1E</span>

DNA-directed RNA polymerase I subunit RPA49 is an enzyme that in humans is encoded by the POLR1E gene.

<span class="mw-page-title-main">POLR1B</span>

DNA-directed RNA polymerase I subunit RPA2 is an enzyme that in humans is encoded by the POLR1B gene.

<span class="mw-page-title-main">EIF3EIP</span>

Eukaryotic translation initiation factor 3 subunit L (eIF3l), less commonly known as EIF3EIP, is a protein that in humans is encoded by the EIF3L gene.

<span class="mw-page-title-main">TAF1C</span> Protein-coding gene in the species Homo sapiens

TATA box-binding protein-associated factor RNA polymerase I subunit C is an enzyme that in humans is encoded by the TAF1C gene.

<span class="mw-page-title-main">TAF1A</span> Protein-coding gene in the species Homo sapiens

TATA box-binding protein-associated factor RNA polymerase I subunit A is an enzyme that in humans is encoded by the TAF1A gene.

<span class="mw-page-title-main">Transcription termination factor, RNA polymerase I</span> Protein-coding gene in the species Homo sapiens

Transcription termination factor 1 is a protein that in humans is encoded by the TTF1 gene.

<span class="mw-page-title-main">POLR1A</span>

DNA-directed RNA polymerase I subunit RPA1 is an enzyme that in humans is encoded by the POLR1A gene.

<span class="mw-page-title-main">ZNF143</span> Protein-coding gene

Zinc finger protein 143 is a protein that in humans is encoded by the ZNF143 gene.

<span class="mw-page-title-main">TAF1B</span>

TATA box-binding protein-associated factor RNA polymerase I subunit B is an enzyme that in humans is encoded by the TAF1B gene.

<span class="mw-page-title-main">PTRF</span> Protein-coding gene in the species Homo sapiens

Polymerase I and transcript release factor, also known as Cavin1, Cavin-1 or PTRF, is a protein which in humans is encoded by the PTRF gene.

<span class="mw-page-title-main">BAZ2A</span> Protein-coding gene in the species Homo sapiens

Bromodomain adjacent to zinc finger domain protein 2A is a protein that in humans is encoded by the BAZ2A gene.

References

  1. 1 2 3 ENSG00000278494 GRCh38: Ensembl release 89: ENSG00000085721, ENSG00000278494 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022682 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Moorefield B, Greene EA, Reeder RH (May 2000). "RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and human". Proc. Natl. Acad. Sci. U.S.A. 97 (9): 4724–9. Bibcode:2000PNAS...97.4724M. doi: 10.1073/pnas.080063997 . PMC   18300 . PMID   10758157.
  6. 1 2 Miller G, Panov KI, Friedrich JK, Trinkle-Mulcahy L, Lamond AI, Zomerdijk JC (Mar 2001). "hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters". EMBO J. 20 (6): 1373–82. doi:10.1093/emboj/20.6.1373. PMC   145519 . PMID   11250903.
  7. "Entrez Gene: RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)".

Further reading