Roseburia inulinivorans

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Roseburia inulinivorans
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Bacteria
Kingdom: Bacillati
Phylum: Bacillota
Class: Clostridia
Order: Eubacteriales
Family: Lachnospiraceae
Genus: Roseburia
Species:
R. inulinivorans
Binomial name
Roseburia inulinivorans
Duncan et al. 2006

Roseburia inulinivorans is a bacterium first isolated from human faeces. It is anaerobic, Gram-positive or Gram-variable, slightly curved rod-shaped and motile. The cells range in size from 0.5-1.5 to 5.0 micrometres. A2-194(T) (=DSM 16841(T) =NCIMB 14030(T)) is the type strain. [1]

Contents

The abundance of Roseburia inulinivorans has been reported to decline with age and has been associated with greater muscle strength in humans. In mice, there is strong evidence that increasing its levels enhances muscle strength, likely through mechanisms involving modulation of intestinal amino acid availability, alterations in muscle purine metabolism, and an increase in type II muscle fibers. These adaptations have been associated with improvements in muscle performance, with reported increases in strength of up to 30%. However, further studies in humans are required to determine whether these effects are translatable. [2]

References

  1. Sylvia H. Duncan; Rustam I. Aminov; Karen P. Scott; Petra Louis; Thaddeus B. Stanton & Harry J. Flint (October 2006). "Proposal of Roseburia faecis sp. nov., Roseburia hominis sp. nov. and Roseburia inulinivorans sp. nov., based on isolates from human faeces". International Journal of Systematic and Evolutionary Microbiology . 56 (Pt 10): 2437–2441. doi: 10.1099/ijs.0.64098-0 . PMID   17012576.
  2. Martinez-Tellez, Borja; Schönke, Milena; Kovynev, Artemiy; Garcia-Dominguez, Esther; Ortiz-Alvarez, Lourdes; Verhoeven, Aswin; Gacesa, Ranko; Vich Vila, Arnau; Ducarmon, Quinten Raymond; Jimenez-Pavon, David; Gomez-Cabrera, Maria Del Carmen; Weersma, Rinse K.; Smits, Wiep-Klaas; Giera, Martin; Ruiz, Jonatan R. (2026-03-10). "Roseburia inulinivorans increases muscle strength". Gut: gutjnl–2025–336980. doi:10.1136/gutjnl-2025-336980. ISSN   1468-3288. PMID   41806991.

Further reading