SF3B5

SF3B5
Identifiers
Aliases	SF3B5 , SF3b10, Ysf3, splicing factor 3b subunit 5
External IDs	OMIM: 617847; MGI: 1913375; HomoloGene: 41825; GeneCards: SF3B5; OMA:SF3B5 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6q24.2 Start 144,094,884 bp [1] End 144,095,573 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 A2 Start 12,881,087 bp [2] End 12,884,927 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary mucosa of transverse colon granulocyte right adrenal gland left adrenal cortex right adrenal cortex olfactory zone of nasal mucosa body of pancreas skin of leg skin of abdomen Top expressed in internal carotid artery endocardial cushion efferent ductule abdominal wall mandibular prominence external carotid artery maxillary prominence renal corpuscle endothelial cell of lymphatic vessel migratory enteric neural crest cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding Cellular component U12-type spliceosomal complex spliceosomal complex precatalytic spliceosome nucleus U2 snRNP nucleoplasm U2-type precatalytic spliceosome Biological process mRNA processing RNA splicing mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83443 66125 Ensembl ENSG00000169976 ENSMUSG00000078348 UniProt Q9BWJ5 Q923D4 RefSeq (mRNA) NM_031287 NM_175102 RefSeq (protein) NP_112577 NP_780311 Location (UCSC) Chr 6: 144.09 – 144.1 Mb Chr 10: 12.88 – 12.88 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Splicing factor 3B subunit 5 is a protein that in humans is encoded by the SF3B5 gene. ^{[5] [6]}

The protein is a part of splicing factor 3b.

References

1. GRCh38: Ensembl release 89: ENSG00000169976 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000078348 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Luhrmann R (Sep 2002). "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein". EMBO J. 21 (18): 4978–88. doi:10.1093/emboj/cdf480. PMC   126279 . PMID   12234937.
6. "Entrez Gene: SF3B5 splicing factor 3b, subunit 5, 10kDa".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.