SH3BGR

SH3BGR
Identifiers
Aliases	SH3BGR , 21-GARP, SH3 domain binding glutamate rich protein
External IDs	OMIM: 602230; HomoloGene: 137201; GeneCards: SH3BGR; OMA:SH3BGR - orthologs
Gene location (Human) Chr. Chromosome 21 (human) [1] Band 21q22.2 Start 39,445,855 bp [1] End 39,515,506 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle skeletal muscle tissue muscle of thigh left ventricle apex of heart right auricle of heart right coronary artery ascending aorta Descending thoracic aorta left coronary artery n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SH3 domain binding Cellular component cytosol Biological process positive regulation of signal transduction protein-containing complex assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6450 n/a Ensembl ENSG00000185437 n/a UniProt P55822 n/a RefSeq (mRNA) NM_001001713 NM_007341 NM_001317740 NM_001317741 NM_001317742 n/a RefSeq (protein) NP_001001713 NP_001304669 NP_001304670 NP_001304671 NP_031367 n/a Location (UCSC) Chr 21: 39.45 – 39.52 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

SH3 domain-binding glutamic acid-rich protein is a protein that in humans is encoded by the SH3BGR gene. ^{[3] [4]}

See also

• Glutamic acid
• SH3 domain
• SH3BGRL
• SH3BGRL3

References

1. GRCh38: Ensembl release 89: ENSG00000185437 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Scartezzini P, Egeo A, Colella S, Fumagalli P, Arrigo P, Nizetic D, Taramelli R, Rasore-Quartino A (Mar 1997). "Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle". Hum Genet. 99 (3): 387–92. doi:10.1007/s004390050377. PMID   9050928. S2CID   40468995.
4. "Entrez Gene: SH3BGR SH3 domain binding glutamic acid-rich protein".

Further reading

• Hu YH, Warnatz HJ, Vanhecke D, et al. (2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC Genomics. 7: 155. doi: 10.1186/1471-2164-7-155 . PMC   1526728 . PMID   16780588.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Sandri C, Di Lisi R, Picard A, et al. (2004). "Heart morphogenesis is not affected by overexpression of the Sh3bgr gene mapping to the Down syndrome heart critical region". Hum. Genet. 114 (5): 517–9. doi:10.1007/s00439-004-1088-8. PMID   14767758. S2CID   9986804.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Jiang LQ, Wen SJ, Wang HY, Chen LY (2003). "Screening the proteins that interact with calpain in a human heart cDNA library using a yeast two-hybrid system". Hypertens. Res. 25 (4): 647–52. doi: 10.1291/hypres.25.647 . PMID   12358155.
• Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. Bibcode:2000Natur.405..311H. doi: 10.1038/35012518 . PMID   10830953.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.