SH3GLB2

Last updated
SH3GLB2
Identifiers
Aliases SH3GLB2 , PP6569, PP9455, RRIG1, SH3 domain containing GRB2 like endophilin B2, SH3 domain containing GRB2 like, endophilin B2
External IDs OMIM: 609288 MGI: 2385131 HomoloGene: 10595 GeneCards: SH3GLB2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289709
NM_001289710
NM_139302
NM_001346806
NM_001362888

Contents

RefSeq (protein)

NP_001276638
NP_001276639
NP_001333735
NP_647463
NP_001349817

Location (UCSC) Chr 9: 129.01 – 129.03 Mb Chr 2: 30.34 – 30.36 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Endophilin-B2 is a protein that in humans is encoded by the SH3GLB2 gene. [5] [6]

Interactions

SH3GLB2 has been shown to interact with SH3GLB1 [5] and SH3KBP1. [7] [8]

Related Research Articles

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SOS1

Son of sevenless homolog 1 is a protein that in humans is encoded by the SOS1 gene.

CBL (gene) mammalian gene

Cbl is a mammalian gene encoding the protein CBL which is an E3 ubiquitin-protein ligase involved in cell signalling and protein ubiquitination. Mutations to this gene have been implicated in a number of human cancers, particularly acute myeloid leukaemia.

SH3KBP1

SH3 domain-containing kinase-binding protein 1 is an adaptor protein that in humans is encoded by the SH3KBP1 gene.

CBLB (gene)

CBL-B is an E3 ubiquitin-protein ligase that in humans is encoded by the CBLB gene. CBLB is a member of the CBL gene family.

TAS1R1

Taste receptor type 1 member 1 is a protein that in humans is encoded by the TAS1R1 gene.

TAS1R3

Taste receptor type 1 member 3 is a protein that in humans is encoded by the TAS1R3 gene. The TAS1R3 gene encodes the human homolog of mouse Sac taste receptor, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharin, and other sweeteners.

RIPK2

Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene.

SH3GL2

Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.

SFRS4

Splicing factor, arginine/serine-rich 4 is a protein that in humans is encoded by the SFRS4 gene.

SH3GL3

Endophilin-A3 is a protein that in humans is encoded by the SH3GL3 gene.

SH3GL1

Endophilin-A2 is a protein that in humans is encoded by the SH3GL1 gene.

SH3GLB1

Endophilin-B1 is a protein that in humans is encoded by the SH3GLB1 gene.

CBLC

Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene.

OSTF1

Osteoclast-stimulating factor 1 is a protein that in humans is encoded by the OSTF1 gene.

SPRY1

Protein sprouty homolog 1 is a protein that in humans is encoded by the SPRY1 gene.

FOXK2

Forkhead box protein K2 is a protein that in humans is encoded by the FOXK2 gene.

HES5

Transcription factor HES-5 is a protein that in humans is encoded by the HES5 gene.

MMACHC

Methylmalonic aciduria and homocystinuria type C protein (MMACHC) is a protein that in humans is encoded by the MMACHC gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000148341 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026860 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 Pierrat B, Simonen M, Cueto M, Mestan J, Ferrigno P, Heim J (February 2001). "SH3GLB, a new endophilin-related protein family featuring an SH3 domain". Genomics. 71 (2): 222–34. doi:10.1006/geno.2000.6378. PMID   11161816.
  6. "Entrez Gene: SH3GLB2 SH3-domain GRB2-like endophilin B2".
  7. Petrelli A, Gilestro GF, Lanzardo S, Comoglio PM, Migone N, Giordano S (March 2002). "The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met". Nature . 416 (6877): 187–90. Bibcode:2002Natur.416..187P. doi:10.1038/416187a. PMID   11894096. S2CID   4389099.
  8. Soubeyran P, Kowanetz K, Szymkiewicz I, Langdon WY, Dikic I (March 2002). "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors". Nature . 416 (6877): 183–7. Bibcode:2002Natur.416..183S. doi:10.1038/416183a. PMID   11894095. S2CID   635702.

Further reading