SNAPC2

SNAPC2
Identifiers
Aliases	SNAPC2 , PTFDELTA, SNAP45, small nuclear RNA activating complex polypeptide 2
External IDs	OMIM: 605076 MGI: 1914861 HomoloGene: 2318 GeneCards: SNAPC2
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.2 Start 7,920,338 bp [1] End 7,923,250 bp [1]
Gene location (Mouse) Chr. Chromosome 8 (mouse) [2] Band 8|8 A1.1 Start 4,253,080 bp [2] End 4,256,220 bp [2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity Cellular component • cell nucleus • nucleoplasm • cytosol • nuclear body Biological process • snRNA transcription • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • transcription, DNA-templated • transcription from RNA polymerase III promoter • snRNA transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6618	102209
Ensembl	ENSG00000104976	ENSMUSG00000011837
UniProt	Q13487	Q91XA5
RefSeq (mRNA)	NM_003083	NM_133968
RefSeq (protein)	NP_003074	NP_598729
Location (UCSC)	Chr 19: 7.92 – 7.92 Mb	Chr 8: 4.25 – 4.26 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

snRNA-activating protein complex subunit 2 is a protein that in humans is encoded by the SNAPC2 gene. ^{[5] [6]}

Interactions

SNAPC2 has been shown to interact with SNAPC4. ^{[7] [8]}

References

1. GRCh38: Ensembl release 89: ENSG00000104976 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000011837 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sadowski CL, Henry RW, Kobayashi R, Hernandez N (April 1996). "The SNAP45 subunit of the small nuclear RNA (snRNA) activating protein complex is required for RNA polymerase II and III snRNA gene transcription and interacts with the TATA box binding protein". Proceedings of the National Academy of Sciences of the United States of America. 93 (9): 4289–93. Bibcode:1996PNAS...93.4289S. doi:10.1073/pnas.93.9.4289. PMC   39528 . PMID   8633057.
6. "Entrez Gene: SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa".
7. Wong MW, Henry RW, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N (January 1998). "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1". Molecular and Cellular Biology. 18 (1): 368–77. doi:10.1128/mcb.18.1.368. PMC   121507 . PMID   9418884.
8. Ma B, Hernandez N (February 2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". The Journal of Biological Chemistry. 276 (7): 5027–35. doi: 10.1074/jbc.M009301200 . PMID   11056176.

Further reading

• Henry RW, Sadowski CL, Kobayashi R, Hernandez N (April 1995). "A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III". Nature. 374 (6523): 653–6. Bibcode:1995Natur.374..653H. doi:10.1038/374653a0. PMID   7715707. S2CID   4325527.
• Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Yoon JB, Roeder RG (January 1996). "Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein". Molecular and Cellular Biology. Advances in Molecular and Cell Biology. 16 (1): 1–9. doi:10.1016/S1569-2558(08)60061-2. ISBN   978-0-7623-0143-0. PMC   230972 . PMID   8524284.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Wong MW, Henry RW, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N (January 1998). "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1". Molecular and Cellular Biology. 18 (1): 368–77. doi:10.1128/mcb.18.1.368. PMC   121507 . PMID   9418884.
• Ma B, Hernandez N (February 2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". The Journal of Biological Chemistry. 276 (7): 5027–35. doi: 10.1074/jbc.M009301200 . PMID   11056176.
• Acierno JS, Kennedy JC, Falardeau JL, Leyne M, Bromley MC, Colman MW, Sun M, Bove C, Ashworth LK, Chadwick LH, Schiripo T, Ma S, Goldin E, Schiffmann R, Slaugenhaupt SA (April 2001). "A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2". Genomics. 73 (2): 203–10. doi:10.1006/geno.2001.6526. PMID   11318610.
• Hinkley CS, Hirsch HA, Gu L, LaMere B, Henry RW (May 2003). "The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition". The Journal of Biological Chemistry. 278 (20): 18649–57. doi: 10.1074/jbc.M204247200 . PMID   12621023.