STK25

Last updated

STK25
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases STK25 , SOK1, YSK1, serine/threonine kinase 25
External IDs OMIM: 602255; MGI: 1891699; HomoloGene: 48428; GeneCards: STK25; OMA:STK25 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021537

RefSeq (protein)

NP_067512

Location (UCSC) Chr 2: 241.49 – 241.51 Mb Chr 1: 93.55 – 93.59 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Serine/threonine-protein kinase 25 is an enzyme that in humans is encoded by the STK25 gene. [5] [6] [7] [8]

Contents

Interactions

STK25 has been shown to interact with STRN, [9] PDCD10 [10] and MOBKL3. [9]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000115694 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026277 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Pombo CM, Bonventre JV, Molnar A, Kyriakis J, Force T (Jan 1997). "Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway". EMBO J. 15 (17): 4537–46. doi:10.1002/j.1460-2075.1996.tb00831.x. PMC   452183 . PMID   8887545.
  6. Osada S, Izawa M, Saito R, Mizuno K, Suzuki A, Hirai S, Ohno S (Jun 1997). "YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways". Oncogene. 14 (17): 2047–57. doi:10.1038/sj.onc.1201043. PMID   9160885. S2CID   27210425.
  7. Preisinger C, Short B, De Corte V, Bruyneel E, Haas A, Kopajtich R, Gettemans J, Barr FA (Mar 2004). "YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta". J Cell Biol. 164 (7): 1009–20. doi:10.1083/jcb.200310061. PMC   2172068 . PMID   15037601.
  8. "Entrez Gene: STK25 serine/threonine kinase 25 (STE20 homolog, yeast)".
  9. 1 2 Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC (January 2009). "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein". Mol. Cell. Proteomics. 8 (1): 157–71. doi: 10.1074/mcp.M800266-MCP200 . PMC   2621004 . PMID   18782753.
  10. Rual JF, Venkatesan K, Hao T, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.

Further reading