SYPL1

SYPL1
Identifiers
Aliases	SYPL1 , H-SP1, SYPL, synaptophysin like 1
External IDs	OMIM: 616665 MGI: 108081 HomoloGene: 4915 GeneCards: SYPL1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	106,112,576 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	33,029,859 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; parotid gland; ; minor salivary gland; ; cavity of mouth; ; vagina; ; thymus; ; palpebral conjunctiva; ; gallbladder; ; rectum; ; hair follicle;
	Top expressed in
	spermatid; ; conjunctival fornix; ; corneal stroma; ; ascending aorta; ; parotid gland; ; crypt of lieberkuhn of small intestine; ; aortic valve; ; seminal vesicula; ; triceps brachii muscle; ; sternocleidomastoid muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transporter activity ; syntaxin-1 binding ;
Cellular component	synaptic vesicle ; secretory granule ; cytoplasmic vesicle membrane ; membrane ; melanosome ; cytoplasmic vesicle ; integral component of synaptic vesicle membrane ; integral component of membrane ; integral component of plasma membrane ; extracellular exosome ; synaptic vesicle membrane ;
Biological process	chemical synaptic transmission ; transport ;
	Sources:Amigo / QuickGO
Orthologs
	6856
	19027
	ENSG00000008282
	ENSMUSG00000020570
	Q16563
	O09117
	NM_006754 ; NM_182715
	NM_013635 ; NM_198710
NP_006745 ; NP_874384 ; NP_001368839 ; NP_001368840 ; NP_001368841 ;
	NP_001368842 ; NP_001368844 ; NP_001368845 ; NP_001368846 ; NP_001368847 ; NP_001368848 ; NP_001368849 ; NP_001368850
	NP_038663 ; NP_942003
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Synaptophysin-like protein 1 is a protein that in humans is encoded by the SYPL1 gene.^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000008282 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020570 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: SYPL1 synaptophysin-like 1".

Zhong CZ, Hayzer DJ, Runge MS (1992). "Molecular cloning of a cDNA encoding a novel protein related to the neuronal vesicle protein synaptophysin". Biochim. Biophys. Acta. 1129 (2): 235–8. doi:10.1016/0167-4781(92)90495-l. PMID 1730063.
Leube RE (1994). "Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human". Differentiation. 56 (3): 163–71. doi:10.1046/j.1432-0436.1994.5630163.x. PMID 8034131.
Haass NK, Kartenbeck MA, Leube RE (1996). "Pantophysin is a ubiquitously expressed synaptophysin homologue and defines constitutive transport vesicles". J. Cell Biol. 134 (3): 731–46. doi:10.1083/jcb.134.3.731. PMC 2120938 . PMID 8707851.
Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi: 10.1101/gr.8.11.1097 . PMID 9847074.
Windoffer R, Borchert-Stuhlträger M, Haass NK, et al. (1999). "Tissue expression of the vesicle protein pantophysin". Cell Tissue Res. 296 (3): 499–510. doi:10.1007/s004410051310. PMID 10370136. S2CID 6765747.
Brooks CC, Scherer PE, Cleveland K, et al. (2000). "Pantophysin is a phosphoprotein component of adipocyte transport vesicles and associates with GLUT4-containing vesicles". J. Biol. Chem. 275 (3): 2029–36. doi: 10.1074/jbc.275.3.2029 . PMID 10636906.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961 . PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi: 10.1038/nature01782 . PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Chi A, Valencia JC, Hu ZZ, et al. (2007). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes". J. Proteome Res. 5 (11): 3135–44. doi:10.1021/pr060363j. PMID 17081065.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000008282 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020570 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SYPL1 synaptophysin-like 1".

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SYPL1

Related Research Articles

References

Further reading