Ronald Mark Evans is an American Biologist, Professor and Head of the Salk’s Gene Expression Laboratory, and the March of Dimes Chair in Molecular and Developmental Biology at the Salk Institute for Biological Studies in La Jolla, California and a Howard Hughes Medical Institute Investigator. Dr. Ronald M. Evans is known for his original discoveries of nuclear hormone receptors (NR), a special class of transcriptional factor, and the elucidation of their universal mechanism of action, a process that governs how lipophilic hormones and drugs regulate virtually every developmental and metabolic pathway in animals and humans. Nowadays, NRs are among the most widely investigated group of pharmaceutical targets in the world, already yielding benefits in drug discovery for cancer, muscular dystrophies, osteoporosis, type II diabetes, obesity, and cardiovascular diseases. His current research focuses on the function of nuclear hormone signaling and their function in metabolism and cancer.
Susumu Tonegawa is a Japanese scientist who was the sole recipient of the Nobel Prize for Physiology or Medicine in 1987 for his discovery of V(D)J recombination, the genetic mechanism which produces antibody diversity. Although he won the Nobel Prize for his work in immunology, Tonegawa is a molecular biologist by training and he again changed fields following his Nobel Prize win; he now studies neuroscience, examining the molecular, cellular and neuronal basis of memory formation and retrieval.
Osaka University, abbreviated as OU or Handai (阪大), is a national research university in Osaka, Japan. The university traces its roots back to Edo-era institutions Tekijuku (1838) and Kaitokudo (1724), and was officially established in 1931 as the sixth of the Imperial Universities in Japan, with two faculties: science and medicine. Following the post-war educational reform, it merged with three pre-war higher schools, reorganizing as a comprehensive university with five faculties: science, medicine, letters, law and economics, and engineering. After the merger with Osaka University of Foreign Studies in 2007, Osaka University became the largest national university in Japan by undergraduate enrollment.
Tadamitsu Kishimoto is a Japanese immunologist known for research on IgM and cytokines, most famously, interleukin 6.
Masaru Tomita is a Japanese scientist in the fields of systems biology and computer science, best known as the founder of the E-Cell simulation system and/or the inventor of GLR parser algorithm. He served a professor of Keio University, Director of the Institute for Advanced Biosciences, and the founder and board member of various spinout companies, including Human Metabolome Technologies, Inc. and Spiber Inc. He is also the co-founder and on the board of directors of The Metabolomics Society. His father was the renowned composer and synthesiser pioneer Isao Tomita.
The Gruber Prize in Neuroscience, established in 2004, is one of three international awards worth US$500,000 made by the Gruber Foundation, a non-profit organization based in Yale University in New Haven, Connecticut.
Koji Nakanishi was a Japanese chemist who studied bioorganic chemistry and natural products. He served as Centennial Professor of Chemistry and chair of the Chemistry Department at Columbia University.
Osamu Hayaishi MJA, was a Japanese biochemist, physiologist, and military physician. He discovered Oxygenases at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health in 1955.
Metabotropic glutamate receptor 7 is a protein that in humans is encoded by the GRM7 gene.
Shizuo Akira is a professor at the Department of Host Defense, Osaka University, Japan. He has made ground-breaking discoveries in the field of immunology, most significantly in the area of innate host defense mechanisms.
Richard Lewis Huganir is a Bloomberg Distinguished Professor in the Departments of Neuroscience and Psychological and Brain Sciences, Director of the Solomon H. Snyder Department of Neuroscience, and co-director of the Johns Hopkins Medicine Brain Science Institute at the Johns Hopkins University School of Medicine. He has joint appointments in the Department of Biological Chemistry and the Department of Pharmacology and Molecular Sciences in the Johns Hopkins School of Medicine.
Thomas Christian Südhof, ForMemRS, is a German-American biochemist known for his study of synaptic transmission. Currently, he is a professor in the school of medicine in the department of molecular and cellular physiology, and by courtesy in neurology, and in psychiatry and behavioral sciences at Stanford University.
Karl Alexander Deisseroth is an American scientist. He is the D.H. Chen Foundation Professor of Bioengineering and of psychiatry and behavioral sciences at Stanford University.
Yoshinori Ohsumi is a Japanese cell biologist specializing in autophagy, the process that cells use to destroy and recycle cellular components. Ohsumi is a professor at Tokyo Institute of Technology's Institute of Innovative Research. He received the Kyoto Prize for Basic Sciences in 2012, the 2016 Nobel Prize in Physiology or Medicine, and the 2017 Breakthrough Prize in Life Sciences for his discoveries of mechanisms for autophagy.
Shigekazu Nagata is a Japanese biochemist, best known for research on apoptosis, the process of programmed cell death occurring in multi-cellular organisms.
Tasuku Honjo is a Japanese physician-scientist and immunologist. He won the 2018 Nobel Prize in Physiology or Medicine and is best known for his identification of programmed cell death protein 1 (PD-1). He is also known for his molecular identification of cytokines: IL-4 and IL-5, as well as the discovery of activation-induced cytidine deaminase (AID) that is essential for class switch recombination and somatic hypermutation.
Shimon Sakaguchi is an immunologist and a Distinguished Professor of Osaka University. He is best known for the discovery of regulatory T cells and to describe their role in the immune system. This discovery is used in the treatment of cancer and autoimmune diseases.
Iain William Mattaj FRS FRSE is a British scientist and Honorary Professor at Heidelberg University in Germany. From 2005 to 2018 he was Director General of the European Molecular Biology Laboratory (EMBL). He stepped down from the position at the end of 2018 following his appointment to Human Technopole. In January 2019 he took office as the first Director of Human Technopole, the new Italian institute for life sciences in Milan, Italy.
Stephen F. Heinemann (1939–2014) was a professor of neuroscience at the Salk Institute. He was an early researcher in the field of molecular neuroscience, contributing to the current knowledge of how nerves communicate with each other, and the role of neurotransmitters. Stephen Heinemann died August 6, 2014, of kidney failure.
Masashi Yanagisawa is a Japanese-American molecular biologist and physician, famous for his discovery of the hormone endothelin and the neuropeptide orexin, the absence of which is the cause of narcolepsy. He is currently the Director of the International Institute for Integrative Sleep Medicine, University of Tsukuba, and an adjunct professor at the Department of Molecular Genetics, University of Texas Southwestern Medical Center.
