The National Road was the first major improved highway in the United States built by the federal government. Built between 1811 and 1837, the 620-mile (1,000 km) road connected the Potomac and Ohio Rivers and was a main transport path to the West for thousands of settlers. When improved in the 1830s, it became the second U.S. road surfaced with the macadam process pioneered by Scotsman John Loudon McAdam.
The Great River Road is a collection of state and local roads that follow the course of the Mississippi River through ten states of the United States. They are Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi and Louisiana. It formerly extended north into Canada, serving the provinces of Ontario and Manitoba. The road is designated as both a National Scenic Byway and an All-American Road in several states along the route.
U.S. Route 22 (US 22) is a major west–east route and one of the original United States Numbered Highways, founded in 1926. It runs from Cincinnati, Ohio, at US 27, US 42, US 127, and US 52 to Newark, New Jersey, at US 1/9 at the Newark Airport Interchange.
East Liverpool is a city in southeastern Columbiana County, Ohio, United States. The population was 9,958 at the 2020 census. It lies along the Ohio River within the Upper Ohio Valley and borders Pennsylvania to the east and West Virginia to the south. East Liverpool is included in the Salem micropolitan area, about 34 miles (55 km) from both Youngstown and downtown Pittsburgh.
Midland is a borough located along the Ohio River in western Beaver County, Pennsylvania, United States. As of the 2020 census, the population was 2,430. It is part of the Pittsburgh metropolitan area. Founded in 1906, it was initially a company town surrounding the Crucible Steel Company's Midland Works.
Shippingport is a borough in western Beaver County, Pennsylvania, United States, located along the Ohio River. The population was 159 at the 2020 census. It is part of the Pittsburgh metropolitan area. Shippingport is home to the Beaver Valley Nuclear Power Station, and formerly the Bruce Mansfield Power Plant and Shippingport Atomic Power Station, the world's first full-scale atomic electric power plant devoted exclusively to peacetime uses.
U.S. Route 322 is a 494 mi (795.0 km) long, east–west United States Highway, traversing Ohio, Pennsylvania, and New Jersey. The road is a spur of US 22 and one of the original highways from 1926. A portion of it at one time was concurrent with the Lakes-to-Sea Highway.
Interstate 76 (I-76) is an east–west Interstate Highway in the Eastern United States. The highway runs approximately 435 miles (700 km) from an interchange with I-71 west of Akron, Ohio, east to I-295 in Bellmawr, New Jersey. This route is not contiguous with I-76 in Colorado and Nebraska.
The Schuylkill Expressway, locally known as "the Schuylkill", is a freeway through southern Montgomery County and the city of Philadelphia. It is the easternmost segment of Interstate 76 (I-76) in the U.S. state of Pennsylvania. It extends from the Valley Forge interchange of the Pennsylvania Turnpike in King of Prussia, paralleling its namesake Schuylkill River for most of the route, southeast to the Walt Whitman Bridge over the Delaware River in South Philadelphia. It serves as the primary corridor into Philadelphia from points west. Maintenance and planning for most of the highway are administered through Pennsylvania Department of Transportation (PennDOT) District 6, with the Delaware River Port Authority (DRPA) maintaining the approach to the Walt Whitman Bridge.
U.S. Route 30 (US 30) is a U.S. Highway that runs east–west across the southern part of Pennsylvania, passing through Pittsburgh and Philadelphia on its way from the West Virginia state line east to the Benjamin Franklin Bridge over the Delaware River into New Jersey.
Interstate 95 (I-95) is a major north–south Interstate Highway that runs along the East Coast of the United States from Miami, Florida, north to the Canada–United States border at Houlton, Maine. In the state of Pennsylvania, it runs 44.25 miles (71.21 km) from the Delaware state line near Marcus Hook in Delaware County in the southeastern part of the state northeast to the Delaware River–Turnpike Toll Bridge at the New Jersey state line near Bristol in Bucks County, closely paralleling the New Jersey state line for its entire length through Pennsylvania.
Pennsylvania Route 291 is an east–west state route in Pennsylvania that runs from U.S. Route 13 and US 13 Business in Trainer, Delaware County, east to Interstate 76 (I-76) in South Philadelphia near the Walt Whitman Bridge and the South Philadelphia Sports Complex. Except for a short 1-mile (1.6 km) section between the western terminus and the Chester/Trainer line, PA 291 is mostly a four-lane highway. From the western terminus to the eastern part of Chester, the route has a concurrency with US 13. It runs parallel to the Delaware River for much of the route. The route passes through industrial areas near the river in Delaware County, serving Chester, Eddystone, Essington, and Lester. PA 291 enters Philadelphia near the Philadelphia International Airport, at which point it has an interchange with I-95. The route crosses the Schuylkill River on the George C. Platt Memorial Bridge and continues along Penrose Avenue to I-76. It has been designated the Industrial Heritage Highway.
Pennsylvania Route 68 is a 90.036-mile-long (144.899 km) east–west state highway located in western Pennsylvania in the United States. The western terminus of the route is at the Ohio state line west of Glasgow, where PA 68 continues into Ohio as State Route 39. The eastern terminus is at U.S. Route 322 in Clarion. The route runs southwest-northeast across Beaver, Butler, Armstrong, and Clarion counties. PA 68 follows the Ohio River between the Ohio border and Beaver, where it crosses the Beaver River into Rochester and heads northeast away from the Ohio River. The route runs through rural areas to Butler County, where it intersects Interstate 79 (I-79) in Zelienople before serving Evans City and Butler. PA 68 passes through a section of Armstrong County before crossing the Allegheny River into Clarion County. Here, the route passes through Rimersburg and Sligo before it has an interchange with I-80 and continues to its terminus in Clarion.
U.S. Route 1 (US 1) is a major north–south U.S. Route, extending from Key West, Florida, in the south to Fort Kent, Maine, at the Canada–United States border in the north. In the U.S. state of Pennsylvania, US 1 runs for 81 miles (130 km) from the Maryland state line near Nottingham northeast to the New Jersey state line at the Delaware River in Morrisville, through the southeastern portion of the state. The route runs southwest to northeast and serves as a major arterial road through the city of Philadelphia and for many of the suburbs in the Delaware Valley metropolitan area. South of Philadelphia, the road mostly follows the alignment of the Baltimore Pike. Within Philadelphia, it mostly follows Roosevelt Boulevard. North of Philadelphia, US 1 parallels the route of the Lincoln Highway. Several portions of US 1 in Pennsylvania are freeways, including from near the Maryland state line to Kennett Square, the bypass of Media, the concurrency with Interstate 76 and the Roosevelt Expressway in Philadelphia, and between Bensalem Township and the New Jersey state line.
Pennsylvania Route 168 is a highway in Western Pennsylvania that runs for 55 miles (89 km) from PA 18 in Frankfort Springs to PA 208 in Volant. PA 168 intersects or runs concurrently with PA 18 at several points, including New Castle.
U.S. Route 13 (US 13) is a United States Numbered Highway running from Fayetteville, North Carolina, north to Morrisville, Pennsylvania. The route runs for 49.359 miles (79.436 km) through the Delaware Valley in the U.S. state of Pennsylvania. The route enters the state from Delaware in Marcus Hook, Delaware County. It continues northeast through Delaware County, passing through the city of Chester before heading through suburban areas along Chester Pike to Darby. US 13 enters the city of Philadelphia on Baltimore Avenue and runs through West Philadelphia to University City, where it turns north along several city streets before heading east across the Schuylkill River along Girard Avenue. The route turns north and heads to North Philadelphia, where it runs northeast along Hunting Park Avenue. US 13 becomes concurrent with US 1 on Roosevelt Boulevard, continuing into Northeast Philadelphia. US 13 splits southeast on a one-way pair of streets before heading northeast out of the city on Frankford Avenue. The route continues into Bucks County as Bristol Pike, heading northeast to Bristol, where it turns into a divided highway. US 13 becomes a freeway in Tullytown and continues north to its terminus at US 1 in Falls Township, near Morrisville. US 13 roughly parallels Interstate 95 (I-95) through its course in Pennsylvania.
Interstate 70 (I-70) is a portion of the Interstate Highway System that runs from near Cove Fort, Utah, at a junction with I-15 to Baltimore, Maryland. It crosses the Northern Panhandle of West Virginia through Ohio County and the city of Wheeling. This segment is the shortest of all states through which I-70 passes, crossing West Virginia for only 14.45 miles (23.26 km). The Fort Henry Bridge carries I-70 from Wheeling Island across the Ohio River and into downtown Wheeling before the freeway enters the Wheeling Tunnel. I-470, a southerly bypass of Wheeling and the lone auxiliary Interstate Highway in West Virginia, is intersected near Elm Grove. Before crossing into Pennsylvania, I-70 passes The Highlands, a major shopping center in the panhandle, and the Bear Rocks Lake Wildlife Management Area. On average, between 27,000 and 53,000 vehicles use the freeway every day.
Several special routes of U.S. Route 30 exist. In order from west to east they are as follows.
A permanently signed detour route is a type of route which is used temporarily during special circumstances. Various areas have developed these systems as part of incident management. The purpose of these routes is to provide a detour in the event that the parent route is impassable, due to either a traffic jams, traffic collision, or road closure. Sometimes these routes are signed as a prefixed or suffixed numbered road, making them a type of special route.
PA 168 
