Slx1 structure-specific endonuclease subunit homolog b (s. cerevisiae)

Last updated
SLX1B
Identifiers
Aliases SLX1B , GIYD2, Slx1 structure-specific endonuclease subunit homolog b, SLX1 homolog B, structure-specific endonuclease subunit
External IDs OMIM: 615823 MGI: 1915220 HomoloGene: 11434 GeneCards: SLX1B
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178044
NM_024044
NM_001400286
NM_001400287

NM_029420

RefSeq (protein)

NP_001014999
NP_001015000

NP_083696

Location (UCSC) Chr 16: 29.45 – 29.46 Mb Chr 7: 126.29 – 126.29 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) is a protein in humans that is encoded by the SLX1B gene. [5]

This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene. [provided by RefSeq, Nov 2010].

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000181625 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000059772 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)" . Retrieved 2013-05-19.

Further reading