Streptococcus tigurinus

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Streptococcus tigurinus
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Bacteria
Phylum: Bacillota
Class: Bacilli
Order: Lactobacillales
Family: Streptococcaceae
Genus: Streptococcus
Species:
S. tigurinus
Binomial name
Streptococcus tigurinus
Zbinden et al. 2012

Streptococcus tigurinus is a novel member of the genus Streptococcus that was first discovered in 2012 by Swiss researchers. [1]

Contents

Identification

Streptococcus tigrinus is a member of the Gram-positive bacteria family Streptococcaceae and is identifiable by its 16S ribosomal RNA gene analysis. [2] S. tigurinus was initially difficult to study due to its similarity to other bacteria causing it to go unnoticed,[ citation needed ] but it has recently been identified as being the most structurally related to Streptococcus mitis, Streptococcus pneumoniae, Streptococcus pseudopneumoniae, Streptococcus oralis, and Streptococcus intermedius . [2]

Pathogenesis

Streptococcus tigurinus is generally not a normal part of the human bacteria flora and it is currently unknown where its natural habitat is or its potential for colonization. [3] Capable of causing serious infections if it manages to enter the body's bloodstream, usually through open wounds in the mouth, it was first discovered to cause invasive infections after it was isolated from a patient with infective endocarditis.[ citation needed ] It was later detected in the blood and cerebrospinal fluid of 14 other patients with varying types of serious invasive infections such as spondylodiscitis, bacteremia, meningitis, and empyema.[ citation needed ]

Treatment

As S. tigurinus is relatively rare, scientists are still researching the most effective ways to combat the bacterium, with some strains showing resistance to drugs like tetracycline [3] and an enhanced resistance to phagocytosis by macrophages. [4]

Related Research Articles

<i>Streptococcus</i> Genus of bacteria

Streptococcus is a genus of gram-positive coccus or spherical bacteria that belongs to the family Streptococcaceae, within the order Lactobacillales, in the phylum Bacillota. Cell division in streptococci occurs along a single axis, thus when growing they tend to form pairs or chains, which may appear bent or twisted. This differs from staphylococci, which divide along multiple axes, thereby generating irregular, grape-like clusters of cells. Most streptococci are oxidase-negative and catalase-negative, and many are facultative anaerobes.

<span class="mw-page-title-main">Group A streptococcal infection</span> Medical condition

Group A streptococcal infections are a number of infections with Streptococcus pyogenes, a group A streptococcus (GAS). S. pyogenes is a species of beta-hemolytic Gram-positive bacteria that is responsible for a wide range of infections that are mostly common and fairly mild. If the bacteria enter the bloodstream an infection can become severe and life-threatening, and is called an invasive GAS (iGAS).

<i>Streptococcus pneumoniae</i> Species of bacterium

Streptococcus pneumoniae, or pneumococcus, is a Gram-positive, spherical bacteria, alpha-hemolytic member of the genus Streptococcus. They are usually found in pairs (diplococci) and do not form spores and are non motile. As a significant human pathogenic bacterium S. pneumoniae was recognized as a major cause of pneumonia in the late 19th century, and is the subject of many humoral immunity studies.

<span class="mw-page-title-main">Infective endocarditis</span> Medical condition

Infective endocarditis is an infection of the inner surface of the heart, usually the valves. Signs and symptoms may include fever, small areas of bleeding into the skin, heart murmur, feeling tired, and low red blood cell count. Complications may include backward blood flow in the heart, heart failure – the heart struggling to pump a sufficient amount of blood to meet the body's needs, abnormal electrical conduction in the heart, stroke, and kidney failure.

<i>Acinetobacter</i> Genus of bacteria

Acinetobacter is a genus of Gram-negative bacteria belonging to the wider class of Gammaproteobacteria. Acinetobacter species are oxidase-negative, exhibit twitching motility, and occur in pairs under magnification.

Streptococcus suis is a peanut-shaped, Gram-positive bacterium, and an important pathogen of pigs. Endemic in nearly all countries with an extensive pig industry, S. suis is also a zoonotic disease, capable of transmission to humans from pigs.

<span class="mw-page-title-main">Carbapenem</span> Class of highly effective antibiotic agents

Carbapenems are a class of very effective antibiotic agents most commonly used for treatment of severe bacterial infections. This class of antibiotics is usually reserved for known or suspected multidrug-resistant (MDR) bacterial infections. Similar to penicillins and cephalosporins, carbapenems are members of the beta-lactam antibiotics drug class, which kill bacteria by binding to penicillin-binding proteins, thus inhibiting bacterial cell wall synthesis. However, these agents individually exhibit a broader spectrum of activity compared to most cephalosporins and penicillins. Furthermore, carbapenems are typically unaffected by emerging antibiotic resistance, even to other beta-lactams.

<i>Streptococcus agalactiae</i> Species of bacterium

Streptococcus agalactiae is a gram-positive coccus with a tendency to form chains. It is a beta-hemolytic, catalase-negative, and facultative anaerobe.

Bartonellosis is an infectious disease produced by bacteria of the genus Bartonella. Bartonella species cause diseases such as Carrión's disease, trench fever, cat-scratch disease, bacillary angiomatosis, peliosis hepatis, chronic bacteremia, endocarditis, chronic lymphadenopathy, and neurological disorders.

<span class="mw-page-title-main">Subacute bacterial endocarditis</span> Medical condition

Subacute bacterial endocarditis, abbreviated SBE, is a type of endocarditis. Subacute bacterial endocarditis can be considered a form of type III hypersensitivity.

<i>Peptostreptococcus</i> Genus of bacteria

Peptostreptococcus is a genus of anaerobic, Gram-positive, non-spore forming bacteria. The cells are small, spherical, and can occur in short chains, in pairs or individually. They typically move using cilia. Peptostreptococcus are slow-growing bacteria with increasing resistance to antimicrobial drugs. Peptostreptococcus is a normal inhabitant of the healthy lower reproductive tract of women.

Streptococcus mitis is a mesophilic alpha-hemolytic species of Streptococcus that inhabits the oral cavity. It is coccus, gram-positive, catalase negative, and facultative anaerobe. It was previously classified as Streptococcus mitior. Streptococcus mitis is known to cause several medical conditions one of them being infective endocarditis.

<i>Streptococcus oralis</i> Species of bacterium

Streptococcus oralis is a Gram positive viridans streptococcus of the Streptococcus mitis group. S. oralis is one of the pioneer species associated with eubiotic dental pellicle biofilms, and can be found in high numbers on most oral surfaces. It has been, however, found to be an opportunistic pathogen as well.

Cardiobacterium hominis /ˌkɑːrdiəʊbækˈtɪəriəm ˈhɒmɪnɪs/ is a microaerophilic, pleomorphic, fastidious, Gram-negative bacterium part of the Cardiobacteriaceae family and the HACEK group. It is most commonly found in the human microbiota, specifically the oropharyngeal region including the mouth and upper part of the respiratory tract. It is one of the causes of endocarditis, a life-threatening inflammation close to the heart's inner lining and valves. While infections caused by Cardiobacterium hominis are uncommon, various clinical manifestations are linked to the bacterium, including meningitis, septicemia, and bone infections.

Pneumococcal infection is an infection caused by the bacterium Streptococcus pneumoniae.

<i>Streptococcus canis</i> Species of bacterium

Streptococcus canis is a group G beta-hemolytic species of Streptococcus. It was first isolated in dogs, giving the bacterium its name. These bacteria are characteristically different from Streptococcus dysgalactiae, which is a human-specific group G species that has a different phenotypic chemical composition. S. canis is important to the skin and mucosal health of cats and dogs, but under certain circumstances, these bacteria can cause opportunistic infections. These infections were known to afflict dogs and cats prior to the formal description of the species in Devriese et al., 1986. However, additional studies revealed cases of infection in other mammal species, including cattle and even humans. Instances of mortality from S. canis in humans are very low with only a few reported cases, while actual instances of infection may be underreported due to mischaracterizations of the bacteria as S. dysgalactiae. This species, in general, is highly susceptible to antibiotics, and plans to develop a vaccine to prevent human infections are currently being considered.

Streptococcus equinus is a Gram-positive, nonhemolytic, nonpathogenic, lactic acid bacterium of the genus Streptococcus. It is the principal Streptococcus found in the alimentary canal of a horse, and makes up the majority of the bacterial flora in horse feces. Equivalence with Streptococcus bovis has been contested.

Hathewaya histolytica is a species of bacteria found in feces and the soil. It is a motile, gram-positive, aerotolerant anaerobe. H. histolytica is pathogenic in many species, including guinea pigs, mice, and rabbits, and humans. H. histolytica has been shown to cause gas gangrene, often in association with other bacteria species.

<i>Proteus penneri</i> Species of bacterium

Proteus penneri is a Gram-negative, facultatively anaerobic, rod-shaped bacterium. It is an invasive pathogen and a cause of nosocomial infections of the urinary tract or open wounds. Pathogens have been isolated mainly from the urine of patients with abnormalities in the urinary tract, and from stool. P. penneri strains are naturally resistant to numerous antibiotics, including penicillin G, amoxicillin, cephalosporins, oxacillin, and most macrolides, but are naturally sensitive to aminoglycosides, carbapenems, aztreonam, quinolones, sulphamethoxazole, and co-trimoxazole. Isolates of P. penneri have been found to be multiple drug-resistant (MDR) with resistance to six to eight drugs. β-lactamase production has also been identified in some isolates.

<i>Pseudescherichia vulneris</i> Species of bacterium

Pseudescherichia vulneris is a Gram-negative bacterial species. P. vulneris is a fermentative, oxidase-negative, motile rod, which holds characteristics of the family Enterobacteraceae. This bacterium can colonize in the respiratory tract, genital tract, stool, and urinary tract. However, P. vulneris is most often associated with wounds and has been known to colonize open wounds of both humans and animals. This association gave the bacterium its species name, vulneris, which is Latin for wound. It has also been infrequently reported in cases of meningitis. It was identified as Escherichia vulneris in 1982 with a 2017 genomic analysis of its original genus resulting in the creation of its new genus Pseudescherichia.

References

  1. Krzyściak, W; Pluskwa, KK; Jurczak, A; Kościelniak, D (2013). "The pathogenicity of the Streptococcus genus". Eur. J. Clin. Microbiol. Infect. Dis. 32 (11): 1361–76. doi:10.1007/s10096-013-1914-9. PMC   3824240 . PMID   24141975.
  2. 1 2 Zbinden A, et al. (2012). "Streptococcus tigurinus, a Novel Member of the Streptococcus mitis Group, Causes Invasive Infections". J Clin Microbiol. 50 (9): 2969–73. doi:10.1128/JCM.00849-12. PMC   3421813 . PMID   22760039.
  3. 1 2 "Streptcococcus tigurinus". Ccos.ch. Retrieved 15 November 2014.
  4. Veloso TR, et al. (2013). "Streptococcus tigurinus is highly virulent in a rat model of experimental endocarditis". Int J Med Microbiol. 303 (8): 498–504. doi:10.1016/j.ijmm.2013.06.006. PMID   23856340.