Sugar Blues is a book by William Dufty that was released in 1975 and has become a dietary classic. According to the publishers, over 1.6 million copies have been printed. 
Dufty uses the narrative form to delve into the history of sugar and history of medicine. He mentions whistle blowers, such as Semmelweiss, to remind readers of the discontinuities in standard science.
He also delves into the history of Cuba, history of slavery, history of tobacco and tobacco curing to present the sociology of sugar.
The status of sugar, as a product of refining, was compared to drugs:
Later, the euphemism, "made from natural ingredients", is cited as equally applicable to heroin and sugar. (page 148)
The book has 14 chapters, 78 references, five pages of notes, and a 10-page index. The book reviews the history of the world from the point of view of sugar, sounding the alarm of its deleterious and debilitating effects. The chapters are:
Dufty's wife, Gloria Swanson, traveled the United States to promote the book in 1975.
A student of depression avoidance included Sugar Blues as one of its "books which treat either primarily or in particular chapters the role of nutritional and dietary factors in the promotion of mental well-being and prevention of disorder...on the role of diet in particular disorders...functional hypoglycemia (Duffy [sic] 1975)." 
John Lennon’s personal assistant Frederic Seaman described Lennon’s diet in the book The Last Days of John Lennon (1991). When Seaman started in the job, Dufty’s book loomed large: 
A food science educator listed Sugar Blues as a sample text to stimulate critical thinking necessary to become a food scientist:
A practitioner of integrative medicine, Tris Trethart MD, was interviewed by the medical journal Integrative Medicine and he explained: 
Censorship analyst Heather Hendershot and historian Mark Pendergrast have criticized the book for comparing sugar to drugs and suggesting its role in a variety of illnesses including bubonic plague.  
The extreme range of maladies Dufty assigns to sugar has been used to make the indictment appear absurd: 
A macrobiotic diet is a fad diet based on ideas about types of food drawn from Zen Buddhism. The diet tries to balance the supposed yin and yang elements of food and cookware. Major principles of macrobiotic diets are to reduce animal products, eat locally grown foods that are in season, and consume meals in moderation.
Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food. Simple sugars, also called monosaccharides, include glucose, fructose, and galactose. Compound sugars, also called disaccharides or double sugars, are molecules made of two bonded monosaccharides; common examples are sucrose, lactose, and maltose. White sugar is a refined form of sucrose. In the body, compound sugars are hydrolysed into simple sugars.
Human teeth function to mechanically break down items of food by cutting and crushing them in preparation for swallowing and digesting. As such, they are considered part of the human digestive system. Humans have four types of teeth: incisors, canines, premolars, and molars, which each have a specific function. The incisors cut the food, the canines tear the food and the molars and premolars crush the food. The roots of teeth are embedded in the maxilla or the mandible and are covered by gums. Teeth are made of multiple tissues of varying density and hardness.
Gloria May Josephine Swanson was an American actress and producer. She first achieved fame acting in dozens of silent films in the 1920s and was nominated three times for the Academy Award for Best Actress, most famously for her 1950 return in Billy Wilder's Sunset Boulevard, which also earned her a Golden Globe Award.
Tooth enamel is one of the four major tissues that make up the tooth in humans and many other animals, including some species of fish. It makes up the normally visible part of the tooth, covering the crown. The other major tissues are dentin, cementum, and dental pulp. It is a very hard, white to off-white, highly mineralised substance that acts as a barrier to protect the tooth but can become susceptible to degradation, especially by acids from food and drink. Calcium hardens the tooth enamel. In rare circumstances enamel fails to form, leaving the underlying dentin exposed on the surface.
Tooth decay, also known as cavities or caries, is the breakdown of teeth due to acids produced by bacteria. The cavities may be a number of different colors from yellow to black. Symptoms may include pain and difficulty with eating. Complications may include inflammation of the tissue around the tooth, tooth loss and infection or abscess formation.
Dumping syndrome occurs when food, especially sugar, moves too quickly from the stomach to the duodenum—the first part of the small intestine—in the upper gastrointestinal (GI) tract. This condition is also called rapid gastric emptying. It is mostly associated with conditions following gastric or esophageal surgery, though it can also arise secondary to diabetes or to the use of certain medications; it is caused by an absent or insufficiently functioning pyloric sphincter, the valve between the stomach and the duodenum.
William Francis Dufty was an American writer, musician, and activist.
George Ohsawa was a Japanese educator who was the founder of the macrobiotic diet. When living in Europe he went by the pen names of Musagendo Sakurazawa, Nyoiti Sakurazawa, and Yukikazu Sakurazawa. He also used the French first name Georges while living in France, and his name is sometimes also given this spelling. He wrote about 300 books in Japanese and 20 in French. He defined health on the basis of seven criteria: lack of fatigue, good appetite, good sleep, good memory, good humour, precision of thought and action, and gratitude.
Acid erosion is a type of tooth wear. It is defined as the irreversible loss of tooth structure due to chemical dissolution by acids not of bacterial origin. Dental erosion is the most common chronic condition of children ages 5–17, although it is only relatively recently that it has been recognised as a dental health problem. There is generally widespread ignorance of the damaging effects of acid erosion; this is particularly the case with erosion due to consumption of fruit juices because they tend to be considered as healthy. Acid erosion begins initially in the enamel, causing it to become thin, and can progress into dentin, giving the tooth a dull yellow appearance and leading to dentin hypersensitivity.
Hydroxyapatite, also called hydroxylapatite (HA), is a naturally occurring mineral form of calcium apatite with the formula Ca5(PO4)3(OH), but it is usually written Ca10(PO4)6(OH)2 to denote that the crystal unit cell comprises two entities. Hydroxyapatite is the hydroxyl endmember of the complex apatite group. The OH− ion can be replaced by fluoride, chloride or carbonate, producing fluorapatite or chlorapatite. It crystallizes in the hexagonal crystal system. Pure hydroxyapatite powder is white. Naturally occurring apatites can, however, also have brown, yellow, or green colorations, comparable to the discolorations of dental fluorosis.
Dentin hypersensitivity is dental pain which is sharp in character and of short duration, arising from exposed dentin surfaces in response to stimuli, typically thermal, evaporative, tactile, osmotic, chemical or electrical; and which cannot be ascribed to any other dental disease.
A diabetic diet is a diet that is used by people with diabetes mellitus or high blood sugar to minimize symptoms and dangerous complications of long-term elevations in blood sugar.
Seale Harris was an American physician and researcher born in Cedartown, Georgia. He was nicknamed "the Benjamin Franklin of Medicine" by contemporaries for his leadership and writing on a wide range of medical and political topics. Dr. Harris' most celebrated accomplishments were his 1924 hypothesis of hyperinsulinism as a cause of spontaneous hypoglycemia.
Gary Taubes is an American journalist, writer, and low-carbohydrate / high-fat (LCHF) diet advocate. His central claim is that carbohydrates, especially sugar and high-fructose corn syrup, overstimulate the secretion of insulin, causing the body to store fat in fat cells and the liver, and that it is primarily a high level of dietary carbohydrate consumption that accounts for obesity and other metabolic syndrome conditions. He is the author of Nobel Dreams (1987); Bad Science: The Short Life and Weird Times of Cold Fusion (1993); Good Calories, Bad Calories (2007), titled The Diet Delusion (2008) in the UK and Australia; Why We Get Fat: And What to Do About It (2010); The Case Against Sugar (2016); and The Case for Keto: Rethinking Weight Control and the Science and Practice of Low-Carb/High-Fat Eating (2020). Taubes's work often goes against accepted scientific, governmental, and popular tenets such as that obesity is caused by eating too much and exercising too little and that excessive consumption of fat, especially saturated fat in animal products, leads to cardiovascular disease.
The history of sugar has five main phases:
Tooth remineralization is the natural repair process for non-cavitated tooth lesions, in which calcium, phosphate and sometimes fluoride ions are deposited into crystal voids in demineralised enamel. Remineralization can contribute towards restoring strength and function within tooth structure.
A tooth is a hard, calcified structure found in the jaws of many vertebrates and used to break down food. Some animals, particularly carnivores and omnivores, also use teeth to help with capturing or wounding prey, tearing food, for defensive purposes, to intimidate other animals often including their own, or to carry prey or their young. The roots of teeth are covered by gums. Teeth are not made of bone, but rather of multiple tissues of varying density and hardness that originate from the outermost embryonic germ layer, the ectoderm.
Added sugars or free sugars are sugar carbohydrates added to food and beverages at some point before their consumption. These include added carbohydrates, and more broadly, sugars naturally present in honey, syrup, and fruits. They can take multiple chemical forms, including sucrose, glucose (dextrose), and fructose.
Pure, White and Deadly is a 1972 book by John Yudkin, a British nutritionist and former Chair of Nutrition at Queen Elizabeth College, London. Published in New York, it was the first publication by a scientist to anticipate the adverse health effects, especially in relation to obesity and heart disease, of the public's increased sugar consumption. At the time of publication, Yudkin sat on the advisory panel of the British Department of Health's Committee on the Medical Aspects of Food and Nutrition Policy (COMA). He stated his intention in writing the book in the last paragraph of the first chapter: "I hope that when you have read this book I shall have convinced you that sugar is really dangerous."