Suzanne Pfeffer

Last updated
Suzanne Pfeffer
Suzanne Pfeffer 2010 (cropped).jpg
Pfeffer in 2010
Born
Suzanne Ruth Pfeffer
Alma mater University of California, Berkeley (BS)
University of California, San Francisco (PhD)
Scientific career
Fields Parkinson's disease [1]
Institutions Stanford University
Thesis The role of coated vesicles in intracellular transport  (1983)
Website profiles.stanford.edu/suzanne-pfeffer OOjs UI icon edit-ltr-progressive.svg

Suzanne Ruth Pfeffer is an American neuroscientist who is a professor at Stanford University. [2] Her research investigates the molecular mechanisms that cause receptors to be transported between membrane compartments in cells, and she is an expert in Rab GTPases [3] [4] [5] and the molecular basis of inherited Parkinson's disease. [1] [6] [7] She is a Fellow of the American Association for the Advancement of Science, American Academy of Arts and Sciences, the American Society for Biochemistry and Molecular Biology and the American Society for Cell Biology. [8] She is the editor of the Annual Review of Biochemistry . [9]

Contents

Early life and education

Pfeffer has said that she became interested in human physiology as a child. She was an undergraduate student at the University of California, Berkeley, where she became interested in biochemistry. [10] She worked with Michael Chamberlin on binding of Escherichia coli polymerase to T7 DNA polymerase. [11] She moved to the University of California, San Francisco for her graduate studies, where she worked with Regis B. Kelly on synaptic vessels. [10] Her doctoral research investigated the role of coated vesicles in intracellular transport. [12]

Research and career

After her PhD, she moved to Stanford University as a Hay Whitney postdoctoral fellow, where she worked with James Rothman on Golgi transport. [10] [13]

Pfeffer set up her own research program at Stanford University, where she was the first woman to be appointed to the department of biochemistry. [10] Her research investigates the fundamental mechanisms of membrane trafficking. [10] [14]

Selected publications

Awards and honors

References

  1. 1 2 Suzanne Pfeffer publications indexed by Google Scholar OOjs UI icon edit-ltr-progressive.svg
  2. ↑ Suzanne Pfeffer publications from Europe PubMed Central OOjs UI icon edit-ltr-progressive.svg
  3. 1 2 Suzanne R. Pfeffer; James E. Rothman (1 January 1987). "Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi". Annual Review of Biochemistry . 56: 829–852. doi:10.1146/ANNUREV.BI.56.070187.004145. ISSN   0066-4154. PMID   3304148. Wikidata   Q39664981.
  4. 1 2 D Lombardi; Thierry Soldati; M A Riederer; Y Goda; M Zerial; S R Pfeffer (1 February 1993). "Rab9 functions in transport between late endosomes and the trans Golgi network". The EMBO Journal . 12 (2): 677–682. doi:10.1002/J.1460-2075.1993.TB05701.X. ISSN   0261-4189. PMC   413253 . PMID   8440258. Wikidata   Q28609814.
  5. 1 2 S. R. Pfeffer (December 2001). "Rab GTPases: specifying and deciphering organelle identity and function". Trends in Cell Biology . 11 (12): 487–91. doi:10.1016/S0962-8924(01)02147-X. ISSN   0962-8924. PMID   11719054. Wikidata   Q29620750.
  6. ↑ Lin, Fay (1 July 2025). "Enzyme Inhibition Restores Neuron Pathways in a Parkinson's Mouse Model". GEN - Genetic Engineering and Biotechnology News. Retrieved 14 July 2025.
  7. ↑ D'Ardenne, Kimberlee (1 July 2025). "Inhibiting enzyme could halt cell death in Parkinson's disease, study finds". News Center. Stanford Medicine.
  8. ↑ profiles.stanford.edu/suzanne-pfeffer OOjs UI icon edit-ltr-progressive.svg
  9. ↑ "Our Team". Annual Reviews. Retrieved 14 July 2025.
  10. 1 2 3 4 5 Sedwick, Caitlin (2009-04-06). "Suzanne Pfeffer: Sorting through membrane trafficking". Journal of Cell Biology. 185 (1): 4–5. doi:10.1083/jcb.1851pi. ISSN   1540-8140. PMC   2700508 . PMID   19349576.
  11. ↑ Pfeffer, S. R.; Stahl, S. J.; Chamberlin, M. J. (1977-08-10). "Binding of Escherichia coli RNA polymerase to T7 DNA. Displacement of holoenzyme from promoter complexes by heparin". The Journal of Biological Chemistry. 252 (15): 5403–5407. ISSN   0021-9258. PMID   328501.
  12. ↑ Pfeffer, Suzanne Ruth. The role of coated vesicles in intracellular transport. escholarship.org (PhD thesis). OCLC   1020060429. ProQuest   303125660.
  13. ↑ "Suzanne R. Pfeffer, PhD | Parkinson's Disease". michaeljfox.org. Retrieved 2023-07-23.
  14. ↑ Pfeffer, Suzanne; Aivazian, Dikran (2004). "Targeting Rab GTPases to distinct membrane compartments". Nature Reviews Molecular Cell Biology . 5: 886–896.
  15. ↑ Hopkin, Karen (2023-07-23). "Inside AAAS". Science. 258 (5083): 823–824. doi:10.1126/science.258.5083.823 . Retrieved 2024-05-28.
  16. ↑ "ASCB Presidents". ascb.org. Retrieved 2023-07-23.
  17. ↑ "Past presidents". asbmb.org. Retrieved 2023-07-23.
  18. ↑ "Suzanne Pfeffer". amacad.org. American Academy of Arts & Sciences. 2023-07-23. Retrieved 2023-07-23.
  19. ↑ "Suzanne Pfeffer - ASCB". ascb.org. The American Society for Cell Biology. 2024-05-28. Retrieved 2024-05-28.
  20. ↑ "National Academy of Sciences Elects Members and International Members". www.nasonline.org. 30 April 2024. Retrieved 12 May 2024.
  21. ↑ Rottinghaus, Marissa Locke (February 17, 2025). "ASBMB names 2025 fellows". ASBMB Today. Retrieved 14 July 2025.
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