TC2N

TC2N
Identifiers
Aliases	TC2N , C14orf47, C2CD1, MTAC2D1, Tac2-N, tandem C2 domains, nuclear, TAC2N
External IDs	MGI: 1921663; HomoloGene: 12560; GeneCards: TC2N; OMA:TC2N - orthologs
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q32.12 Start 91,779,746 bp [1] End 91,867,536 bp [1]
Gene location (Mouse) Chr. Chromosome 12 (mouse) [2] Band 12|12 E Start 101,611,702 bp [2] End 101,684,782 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas tonsil olfactory zone of nasal mucosa gallbladder Descending thoracic aorta ascending aorta islet of Langerhans epithelium of colon salivary gland minor salivary glands Top expressed in seminal vesicula parotid gland lacrimal gland epithelium of stomach retinal pigment epithelium Epithelium of choroid plexus submandibular gland transitional epithelium of urinary bladder left lung lobe olfactory epithelium More reference expression data BioGPS n/a
Gene ontology Molecular function clathrin binding calcium ion binding syntaxin binding molecular function calcium-dependent phospholipid binding Cellular component nucleus plasma membrane cellular component synapse presynapse Biological process vesicle fusion calcium ion-regulated exocytosis of neurotransmitter regulation of calcium ion-dependent exocytosis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 123036 74413 Ensembl ENSG00000276776 ENSG00000165929 ENSMUSG00000021187 UniProt Q8N9U0 Q91XT6 RefSeq (mRNA) NM_152332 NM_001128595 NM_001128596 NM_001289134 NM_001082976 NM_001286364 NM_028924 RefSeq (protein) NP_001122067 NP_001122068 NP_001276063 NP_689545 NP_001076445 NP_083200 Location (UCSC) Chr 14: 91.78 – 91.87 Mb Chr 12: 101.61 – 101.68 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tandem C2 domains nuclear protein is a protein that in humans is encoded by the TC2N gene. ^{[5] [6]}

References

1. ENSG00000165929 GRCh38: Ensembl release 89: ENSG00000276776, ENSG00000165929 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021187 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Fukuda M, Mikoshiba K (Aug 2001). "Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus". FEBS Lett. 503 (2–3): 217–218. doi: 10.1016/S0014-5793(01)02738-7 . PMID   11526914. S2CID   33045301.
6. "Entrez Gene: MTAC2D1 membrane targeting (tandem) C2 domain containing 1".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415 –D418. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–2144. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.