TNPO2

Last updated
TNPO2
Identifiers
Aliases TNPO2 , IPO3, KPNB2B, TRN2, transportin 2
External IDs OMIM: 603002; MGI: 2384849; HomoloGene: 8381; GeneCards: TNPO2; OMA:TNPO2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_013433
NM_001136195
NM_001136196

RefSeq (protein)
Location (UCSC) Chr 19: 12.7 – 12.72 Mb Chr 8: 85.76 – 85.78 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Transportin-2 is a protein that in humans is encoded by the TNPO2 gene. [5] [6] [7]

Interactions

TNPO2 has been shown to interact with NXF1, [6] NUP98 [8] and Ran (biology). [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000105576 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031691 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G (September 1997). "Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins". The Journal of Cell Biology. 138 (6): 1181–92. doi:10.1083/jcb.138.6.1181. PMC   2132560 . PMID   9298975.
  6. 1 2 3 Shamsher MK, Ploski J, Radu A (October 2002). "Karyopherin beta 2B participates in mRNA export from the nucleus". Proceedings of the National Academy of Sciences of the United States of America. 99 (22): 14195–9. Bibcode:2002PNAS...9914195S. doi: 10.1073/pnas.212518199 . PMC   137860 . PMID   12384575.
  7. "Entrez Gene: TNPO2 transportin 2 (importin 3, karyopherin beta 2b)".
  8. Fontoura BM, Blobel G, Yaseen NR (October 2000). "The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta 2-mediated nuclear import". The Journal of Biological Chemistry. 275 (40): 31289–96. doi: 10.1074/jbc.M004651200 . PMID   10875935.

Further reading