TRA2A | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | TRA2A , AWMS1, HSU53209, transformer 2 alpha homolog | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 602718 MGI: 1933972 HomoloGene: 40866 GeneCards: TRA2A | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Transformer-2 protein homolog alpha is a protein that in humans is encoded by the TRA2A gene. [5] [6] [7]
This gene is a member of the transformer 2 homolog family and encodes a protein with two RS domains and an RRM (RNA recognition motif) domain. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Several alternatively spliced transcript variants of this gene have been described; however, the full-length nature of some of these variants has not been determined. [7]
Transformer-2 protein homolog beta, also known as TRA2B previously known as splicing factor, arginine/serine-rich 10 (SFRS10), is a protein that in humans is encoded by the TRA2B gene.
Nucleolar complex protein 2 homolog is a protein that in humans is encoded by the NOC2L gene.
Protein mago nashi homolog is a protein that in humans is encoded by the MAGOH gene.
Pre-mRNA-processing factor 19 is a protein that in humans is encoded by the PRPF19 gene.
Cyclin dependent kinase 13 is an enzyme that in humans is encoded by the CDK13 gene.
Pumilio homolog 1 is a protein that in humans is encoded by the PUM1 gene.
Eukaryotic initiation factor 4A-III is a protein that in humans is encoded by the EIF4A3 gene.
Pre-mRNA-processing factor 17 is a protein that in humans is encoded by the CDC40 gene.
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 is an enzyme that in humans is encoded by the DHX38 gene.
Cleavage and polyadenylation specificity factor subunit 4 is a protein that in humans is encoded by the CPSF4 gene.
Dual specificity protein kinase CLK3 is an enzyme that in humans is encoded by the CLK3 gene. The CLK3 gene encodes a serine/threonine type protein kinase with a non-conserved N-terminal domain. A long and short isoform result from alternative splicing and coexist in different tissues. Isoform phclk3/152 lacks the kinase domain.
RNA binding motif protein 9 (RBM9), also known as Rbfox2, is a protein which in humans is encoded by the RBM9 gene.
Probable ATP-dependent RNA helicase DDX56 is an enzyme that in humans is encoded by the DDX56 gene.
Pleiotropic regulator 1 is a protein that in humans is encoded by the PLRG1 gene.
60S ribosomal protein L9 is a protein that in humans is encoded by the RPL9 gene.
Nucleolar protein 6 is a protein that in humans is encoded by the NOL6 gene.
Putative rRNA methyltransferase 3 is an enzyme that in humans is encoded by the FTSJ3 gene.
Spermatogenesis-defective protein 39 homolog is a protein that in humans is encoded by the VIPAS39 gene. This protein is involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2. Alternative splicing results in multiple transcript variants.
rRNA-processing protein FCF1 homolog is a protein that in humans is encoded by the FCF1 gene.
tRNA-splicing endonuclease subunit Sen2 is an enzyme that in humans is encoded by the TSEN2 gene.