The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. It is a 13kb gene on chromosome 21q22.3 that has 545 amino acids. AIRE is a transcription factor expressed in the medulla of the thymus. It is part of the mechanism which eliminates self-reactive T cells that would cause autoimmune disease. It exposes T cells to normal, healthy proteins from all parts of the body, and T cells that react to those proteins are destroyed.
Folate transporter 1 is a protein which in humans is encoded by the SLC19A1 gene.
Dual specificity tyrosine-phosphorylation-regulated kinase 1A is an enzyme that in humans is encoded by the DYRK1A gene. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode for at least five different isoforms.
ATP-binding cassette sub-family G member 1 is a protein that in humans is encoded by the ABCG1 gene. It is a homolog of the well-known Drosophila gene white.
Trefoil factor 2 is a protein that in humans is encoded by the TFF2 gene.
DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L gene.
Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial is a protein that in humans is encoded by the GATD3A gene.
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial is an enzyme that in humans is encoded by the NDUFV3 gene.
Ribosomal RNA processing protein 1 homolog A is a protein that in humans is encoded by the RRP1 gene.
Golgi SNAP receptor complex member 2 is a protein that in humans is encoded by the GOSR2 gene.
T-complex protein 10A homolog 2 is a protein that in humans is encoded by the TCP10L gene. It is located next to CFAP298.
ATP synthase subunit O, mitochondrial is an enzyme that in humans is encoded by the ATP5PO gene.
Periodic tryptophan protein 2 homolog is a protein that in humans is encoded by the PWP2 gene.
tRNA -methyltransferase subunit WDR4 is an enzyme subunit that in humans is encoded by the WDR4 gene.
Protein Mis18-alpha is a protein that in humans is encoded by the MIS18A gene.
Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene.
Tetratricopeptide repeat protein 3 is a protein that in humans is encoded by the TTC3 gene.
RWD domain-containing protein 2B is a protein that in humans is encoded by the RWDD2B gene.
Subunit P of phosphatidylinositol N-acetylglucosaminyltransferase is an enzyme subunit that in humans is encoded by the PIGP gene.
Ubiquitin-associated and SH3 domain-containing protein A is a protein that in humans is encoded by the UBASH3A gene.
