TRIM6

Last updated
TRIM6
Identifiers
Aliases TRIM6 , RNF89, tripartite motif containing 6
External IDs OMIM: 607564 MGI: 2137352 HomoloGene: 14381 GeneCards: TRIM6
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_058166
NM_001003818
NM_001198644
NM_001198645

NM_001013616

RefSeq (protein)

NP_001003818
NP_001185573
NP_001185574
NP_477514

NP_001013637

Location (UCSC) Chr 11: 5.6 – 5.61 Mb Chr 7: 103.87 – 103.88 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tripartite motif-containing protein 6 is a protein that in humans is encoded by the TRIM6 gene. [5] [6]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.

The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A read-through transcript transcribed from this gene and TRIM34 has been observed. [6]

Related Research Articles

<span class="mw-page-title-main">TRIM5alpha</span>

Tripartite motif-containing protein 5 also known as RING finger protein 88 is a protein that in humans is encoded by the TRIM5 gene. The alpha isoform of this protein, TRIM5α, is a retrovirus restriction factor, which mediates a species-specific early block to retrovirus infection.

<span class="mw-page-title-main">TRIM28</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1, is a protein that in humans is encoded by the TRIM28 gene.

<span class="mw-page-title-main">TRIM21</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 21, also known as E3 ubiquitin-protein ligase TRIM21, is a protein that in humans is encoded by the TRIM21 gene. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. It is expressed in most human tissues.

<span class="mw-page-title-main">MID1</span> Protein-coding gene in the species Homo sapiens

MID1 is a protein that belongs to the Tripartite motif family (TRIM) and is also known as TRIM18. The MID1 gene is located on the short arm of the X chromosome and loss-of-function mutations in this gene are causative of the X-linked form of a rare developmental disease, Opitz G/BBB Syndrome.

<span class="mw-page-title-main">TRIM24</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing 24 (TRIM24) also known as transcriptional intermediary factor 1α (TIF1α) is a protein that, in humans, is encoded by the TRIM24 gene.

<span class="mw-page-title-main">TRIM27</span> Protein-coding gene in the species Homo sapiens

Zinc finger protein RFP is a protein that in humans is encoded by the TRIM27 gene.

<span class="mw-page-title-main">TRIM37</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 37 is an E3 ubiquitin ligase in humans that is encoded by the TRIM37 gene.

<span class="mw-page-title-main">TRIM25</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 25 is a protein that in humans is encoded by the TRIM25 gene.

<span class="mw-page-title-main">MID2</span> Protein-coding gene in the species Homo sapiens

Midline-2 is a protein that in humans is encoded by the MID2 gene.

<span class="mw-page-title-main">TRIM32</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 32 is a protein that in humans is encoded by the TRIM32 gene. Since its discovery in 1995, TRIM32 has been shown to be implicated in a number of diverse biological pathways.

<span class="mw-page-title-main">TRIM23</span> Protein-coding gene in the species Homo sapiens

GTP-binding protein ARD-1 is a protein that in humans is encoded by the TRIM23 gene.

<span class="mw-page-title-main">TRIM22</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing 22, also known as TRIM22, is a protein which in humans is encoded by the TRIM22 gene.

<span class="mw-page-title-main">TRIM31</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 31 is a protein that in humans is encoded by the TRIM31 gene.

<span class="mw-page-title-main">TRIM33</span> Protein-coding gene in the species Homo sapiens

E3 ubiquitin-protein ligase TRIM33, also known as (ectodermin homolog and tripartite motif-containing 33) is a protein encoded in the human by the gene TRIM33, a member of the tripartite motif family.

<span class="mw-page-title-main">TRIM3</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene.

<span class="mw-page-title-main">TRIM16</span> Gene of the species Homo sapiens

Tripartite motif-containing protein 16 is a protein that in humans is encoded by the TRIM16 gene.

<span class="mw-page-title-main">TRIM9</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.

<span class="mw-page-title-main">TRIM11</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 11 is a protein found in humans that is encoded by the TRIM11 gene.

<span class="mw-page-title-main">TRIM15</span> Protein-coding gene in the species Homo sapiens

Tripartite motif-containing protein 15 is a protein that in humans is encoded by the TRIM15 gene.

<span class="mw-page-title-main">TRIM38</span> Protein-coding gene in the species Homo sapiens

Tripartite motif containing 38 is a protein that in humans is encoded by the TRIM38 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000121236 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000072244 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J. 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC   125245 . PMID   11331580.
  6. 1 2 "Entrez Gene: TRIM6 tripartite motif-containing 6".

Further reading