TTYH3

TTYH3
Identifiers
Aliases	TTYH3 , tweety family member 3
External IDs	OMIM: 608919 MGI: 1925589 HomoloGene: 18431 GeneCards: TTYH3
Gene location (Human)
Chr.	Chromosome 7 (human)
End	2,664,802 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	140,634,786 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; stromal cell of endometrium; ; monocyte; ; prefrontal cortex; ; cingulate gyrus; ; cerebellar vermis; ; appendix; ; Brodmann area 9; ; spleen; ; amygdala;
	Top expressed in
	superior frontal gyrus; ; external carotid artery; ; internal carotid artery; ; piriform cortex; ; molar; ; hand; ; maxillary prominence; ; olfactory bulb; ; medial dorsal nucleus; ; olfactory tubercle;
	More reference expression data
	n/a
Gene ontology
Molecular function	chloride channel activity ; intracellular calcium activated chloride channel activity ; volume-sensitive chloride channel activity ;
Cellular component	integral component of membrane ; plasma membrane ; extracellular exosome ; membrane ; chloride channel complex ;
Biological process	ion transmembrane transport ; chloride transport ; ion transport ; chloride transmembrane transport ; transport ;
	Sources:Amigo / QuickGO
Orthologs
	80727
	78339
	ENSG00000136295
	ENSMUSG00000036565
	Q9C0H2
	Q6P5F7
	NM_025250
	NM_175274 ; NM_001308039 ; NM_001308040
	NP_079526
	NP_001294969 ; NP_780483
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Tweety family member 3 is a protein that in humans is encoded by the TTYH3 gene. ^[5]

Function

This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. [provided by RefSeq, Jul 2008].

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000136295 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000036565 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Tweety family member 3" . Retrieved 2020-04-12.

TTYH3

Contents

Function

Related Research Articles

References

Further reading