| TUBGCP3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | TUBGCP3 , 104p, GCP3, Grip104, SPBC98, Spc98, Spc98p, tubulin gamma complex associated protein 3, ALP6 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 617818 MGI: 2183752 HomoloGene: 4609 GeneCards: TUBGCP3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Gamma-tubulin complex component 3 is a protein that in humans is encoded by the TUBGCP3 gene. [5] [6] [7] It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.
In cell biology, the spindle apparatus refers to the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells. It is referred to as the mitotic spindle during mitosis, a process that produces genetically identical daughter cells, or the meiotic spindle during meiosis, a process that produces gametes with half the number of chromosomes of the parent cell.
Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes, including mitosis. Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division.
Tubulin alpha-1B chain is a protein that in humans is encoded by the TUBA1B gene.
Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.
Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene.
TUBB1 is a gene that codes for the protein Tubulin beta-1 chain in humans.
Gamma-tubulin complex component 2 is a protein that in humans is encoded by the TUBGCP2 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.
Tubulin-folding cofactor B is a protein that in humans is encoded by the TBCB gene.
Katanin p60 ATPase-containing subunit A1 is an enzyme that in humans is encoded by the KATNA1 gene.
Microtubule-associated protein RP/EB family member 3 is a protein that in humans is encoded by the MAPRE3 gene.
Tubulin gamma-2 chain is a protein that in humans is encoded by the TUBG2 gene.
Gamma-tubulin complex component 5 is a protein that in humans is encoded by the TUBGCP5 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.
Gamma-tubulin complex component 6 is a protein that in humans is encoded by the TUBGCP6 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.
Neural precursor cell expressed, developmentally down-regulated 1, also known as Nedd1, is a human gene and encodes the protein NEDD1.
Centrosomal protein of 192 kDa, also known as Cep192, is a protein that in humans is encoded by the CEP192 gene. It is the homolog of the C. elegans and D. melanogaster gene SPD-2.
Centrosomal protein of 164 kDa, also known as CEP164, is a protein that in humans is encoded by the CEP164 gene. Its function appears two be twofold: CEP164 is required for primary cilium formation. Furthermore, it is an important component in the response to DNA damage by UV light.
Centrosomal protein of 76 kDa, also known as CEP76, is a protein that in humans is encoded by the CEP76 gene.
Centrosomal protein of 78 kDa, also known as Cep78, is a protein that in humans is encoded by the CEP78 gene.
Centrosomal protein of 152 kDa, also known as Cep152, is a protein that in humans is encoded by the CEP152 gene. It is the ortholog of the Drosophila melanogaster gene asterless (asl) and both are required for centriole duplication.
Tubulin, gamma complex associated protein 4 is a protein in humans that is encoded by the TUBGCP4 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.
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