Tectonin beta-propeller repeat containing 1

TECPR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4TQ1
Identifiers
Aliases	TECPR1 , tectonin beta-propeller repeat containing 1
External IDs	OMIM: 614781 MGI: 1917631 HomoloGene: 9120 GeneCards: TECPR1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	98,252,232 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	144,160,433 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; pancreatic ductal cell; ; endothelial cell; ; sural nerve; ; trachea; ; middle temporal gyrus; ; prefrontal cortex; ; tibialis anterior muscle; ; blood; ; appendix;
	Top expressed in
	lacrimal gland; ; cerebellar cortex; ; internal carotid artery; ; iris; ; motor neuron; ; thymus; ; substantia nigra; ; external carotid artery; ; adrenal gland; ; interventricular septum;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ; phosphatidylinositol-3-phosphate binding ; lipid binding ;
Cellular component	integral component of membrane ; lysosomal membrane ; autophagosome membrane ; lysosome ; cytoplasmic vesicle ; membrane ; nucleoplasm ; intracellular membrane-bounded organelle ;
Biological process	autophagy ; autophagosome maturation ;
	Sources:Amigo / QuickGO
Orthologs
	25851
	70381
	ENSG00000205356
	ENSMUSG00000066621
	Q7Z6L1
	Q80VP0
	NM_015395
	NM_027410 ; NM_001356992 ; NM_001356993
	NP_056210
	NP_081686 ; NP_001343921 ; NP_001343922
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Tectonin beta-propeller repeat containing 1 is a protein that in humans is encoded by the TECPR1 gene. ^[5]

Function

This gene encodes a tethering factor involved in autophagy. The encoded protein is found at autolysosomes, and is involved in targeting protein aggregates, damaged mitochondria, and bacterial pathogens for autophagy

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000205356 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000066621 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Tectonin beta-propeller repeat containing 1" . Retrieved 2017-01-03.

Tectonin beta-propeller repeat containing 1

Contents

Function

Related Research Articles

References

Further reading