UFSP1

Last updated
UFSP1
Identifiers
Aliases UFSP1 , UFSP, UFM1-specific peptidase 1 (inactive), UFM1 specific peptidase 1 (inactive)
External IDs OMIM: 611481 MGI: 1917490 HomoloGene: 80245 GeneCards: UFSP1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001015072

NM_027356

RefSeq (protein)

NP_001015072

NP_081632

Location (UCSC) Chr 7: 100.89 – 100.89 Mb Chr 5: 137.29 – 137.29 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

UFM1 specific peptidase 1 (inactive) is a protein that in humans is encoded by the UFSP1 gene. [5]

Function

This gene encodes a protein that is similar to other Ufm1-specific proteases. Studies in mouse determined that Ufsp1 releases Ufm1 (ubiquitin-fold modifier 1) from its bound conjugated complexes which also makes it into an active form. Because the human UFSP1 protein is shorter on the N-terminus and lacks a conserved Cys active site, it is predicted to be non-functional.[provided by RefSeq, Nov 2009]. [5]

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000176125 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051502 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: UFM1 specific peptidase 1 (inactive)" . Retrieved 2020-04-15.PD-icon.svg This article incorporates text from this source, which is in the public domain .

This article incorporates text from the United States National Library of Medicine, which is in the public domain.