Varixanthone

Last updated
Varixanthone
Varixanthone.png
Names
Preferred IUPAC name
(2S)-3-Hydroxy-1-[(1R,2S)-11-hydroxy-5-methyl-12-oxo-1,2,3,12-tetrahydropyrano[3,2-a]xanthen-8-yl]-3-methylbutan-2-yl formate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
PubChem CID
  • InChI=1S/C26H28O8/c1-12(2)15-10-32-24-13(3)8-17-20(21(24)22(15)29)23(30)19-16(28)7-6-14(25(19)34-17)9-18(33-11-27)26(4,5)31/h6-8,11,15,18,22,28-29,31H,1,9-10H2,2-5H3/t15-,18+,22-/m1/s1
    Key: GOKVXLNHAYUYGV-FXCLAUTBSA-N
  • CC1=CC2=C(C3=C1OC[C@@H]([C@H]3O)C(=C)C)C(=O)C4=C(C=CC(=C4O2)C[C@@H](C(C)(C)O)OC=O)O
Properties
C26H28O8
Molar mass 468.502 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Varixanthone is an antimicrobial made by the marine fungus Emericella variecolor . [2]

Related Research Articles

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Aspergillus nidulans is one of many species of filamentous fungi in the phylum Ascomycota. It has been an important research organism for studying eukaryotic cell biology for over 50 years, being used to study a wide range of subjects including recombination, DNA repair, mutation, cell cycle control, tubulin, chromatin, nucleokinesis, pathogenesis, metabolism, and experimental evolution. It is one of the few species in its genus able to form sexual spores through meiosis, allowing crossing of strains in the laboratory. A. nidulans is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner. It has septate hyphae with a woolly colony texture and white mycelia. The green colour of wild-type colonies is due to pigmentation of the spores, while mutations in the pigmentation pathway can produce other spore colours.

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Emericella discophora is a fungus. Its ascospores produce wide and entire, nonstellate equatorial crests. It was isolated from soil in Spain.

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Emericella olivicola is a fungus. Its ascospores have star-shaped equatorial crests. It was isolated from olives in Italy.

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Aspergillus unguis is a species of fungus in the genus Aspergillus, and the asexual state (anamorph) of Emericella unguis. Aspergillus unguis is a filamentous soil-borne fungus found on decomposing plant matter and other moist substrates including with building materials and household dust. Aspergillus unguis occurs mainly in tropical and subtropical soils but has also been isolated from various marine and aquatic habitats. The species was first isolated in 1935 by Weill and L. Gaudin. Historically, A. unguis was assigned to the A. nidulans group, a common group of soil-borne fungi due to the resemblance of its ascospores and cleistothecia to those of Emericella nidulans. Aspergillus unguis is distinctive, however, in possessing spicular hyphae. A number of synonyms have been collapsed into this species, including Sterigmatocystis unguis, Aspergillus laokiashanensis and Aspergillus mellinus.

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<span class="mw-page-title-main">Guisinol</span> Chemical compound

Guisinol is an antibacterial depside with the molecular formula C23H25ClO5 that has been isolated from the fungus Aspergillus unguis.

<span class="mw-page-title-main">Anditomin</span> Chemical compound

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References

  1. ↑ "KNApSAcK Metabolite Information - C00045432". www.knapsackfamily.com.
  2. ↑ Malmstrøm, J; Christophersen, C; Barrero, AF; Oltra, JE; Justicia, J; Rosales, A (March 2002). "Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor". Journal of Natural Products. 65 (3): 364–7. doi:10.1021/np0103214. PMID   11908979.
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