Varixanthone

Last updated
Varixanthone
Varixanthone.svg
Names
Preferred IUPAC name
(2S)-3-Hydroxy-1-[(1R,2S)-11-hydroxy-5-methyl-12-oxo-1,2,3,12-tetrahydropyrano[3,2-a]xanthen-8-yl]-3-methylbutan-2-yl formate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
PubChem CID
  • InChI=1S/C26H28O8/c1-12(2)15-10-32-24-13(3)8-17-20(21(24)22(15)29)23(30)19-16(28)7-6-14(25(19)34-17)9-18(33-11-27)26(4,5)31/h6-8,11,15,18,22,28-29,31H,1,9-10H2,2-5H3/t15-,18+,22-/m1/s1
    Key: GOKVXLNHAYUYGV-FXCLAUTBSA-N
  • CC1=CC2=C(C3=C1OC[C@@H]([C@H]3O)C(=C)C)C(=O)C4=C(C=CC(=C4O2)C[C@@H](C(C)(C)O)OC=O)O
Properties
C26H28O8
Molar mass 468.502 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Varixanthone is an antimicrobial made by the marine fungus Emericella variecolor . [2]

Related Research Articles

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Aspergillus nidulans is one of many species of filamentous fungi in the phylum Ascomycota. It has been an important research organism for studying eukaryotic cell biology for over 50 years, being used to study a wide range of subjects including recombination, DNA repair, mutation, cell cycle control, tubulin, chromatin, nucleokinesis, pathogenesis, metabolism, and experimental evolution. It is one of the few species in its genus able to form sexual spores through meiosis, allowing crossing of strains in the laboratory. A. nidulans is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner. It has septate hyphae with a woolly colony texture and white mycelia. The green colour of wild-type colonies is due to pigmentation of the spores, while mutations in the pigmentation pathway can produce other spore colours.

<span class="mw-page-title-main">Depside</span> Class of chemical compounds

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Emericella discophora is a fungus. Its ascospores produce wide and entire, nonstellate equatorial crests. It was isolated from soil in Spain.

Emericella filifera is a fungus. Its ascospores form long appendages that emerge radially from narrow stellate crests. It was isolated from raisins in Argentina.

Emericella olivicola is a fungus. Its ascospores have star-shaped equatorial crests. It was isolated from olives in Italy.

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Emericella is a former genus of fungi.

<span class="mw-page-title-main">Isoemericellin</span> Chemical compound

Isoemericellin is a chemical compound isolated from the marine fungus Emericella variecolor.

<i>Aspergillus versicolor</i> Species of fungus

Aspergillus versicolor is a slow-growing species of filamentous fungus commonly found in damp indoor environments and on food products. It has a characteristic musty odor associated with moldy homes and is a major producer of the hepatotoxic and carcinogenic mycotoxin sterigmatocystin. Like other Aspergillus species, A. versicolor is an eye, nose, and throat irritant.

<i>Aspergillus ustus</i> Species of fungus

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Aspergillus fructiculosus is a species of fungus in the genus Aspergillus. The species was first described in 1965. It has been reported to produce sterigmatocystin.

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Aspergillus filifer is a species of fungus in the genus Aspergillus. It is from the Nidulantes section. The species was first described in 2008. It has been reported to produce shamixanthones and varitriol.

<span class="mw-page-title-main">Guisinol</span> Chemical compound

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References

  1. "KNApSAcK Metabolite Information - C00045432". www.knapsackfamily.com.
  2. Malmstrøm, J; Christophersen, C; Barrero, AF; Oltra, JE; Justicia, J; Rosales, A (March 2002). "Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor". Journal of Natural Products. 65 (3): 364–7. doi:10.1021/np0103214. PMID   11908979.