Vern L. Schramm | |
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Prof. Schramm in his office at the Albert Einstein College of Medicine, April 2004 | |
Born | November 9, 1941 79) | (age
Nationality | United States |
Alma mater | South Dakota State University |
Known for | Enzyme kinetics, Kinetic isotope effect |
Awards | Rudi Lemberg Award, Repligen Award |
Scientific career | |
Fields | Biochemistry |
Doctoral advisor | John F. Morrison |
Vern L. Schramm (born November 9, 1941) is a Professor & Ruth Merns Chair in Biochemistry at the Albert Einstein College of Medicine of Yeshiva University. [1] [2] Schramm was elected to the National Academy of Sciences in 2007. [3] [4] His laboratory's research focuses on the elucidation of enzymatic mechanisms and transition state structure. [4]
This information is then used for the logical design of transition-state inhibitors which have the potential to be new biologically active agents. Some of these are in development to be drugs. Schramm's work has translated basic chemical understanding at the quantum mechanical level to a new approach to drug development. [5]
Schramm earned his bachelor's degree from South Dakota State College, now South Dakota State University. He earned his master's degree in nutrition from Harvard University and his Ph.D. in the mechanism of enzyme action from the Australian National University. [4]
Schramm secured a postdoctoral position at the NASA Ames Research Center after graduation. Later he joined the Temple University School of Medicine as a faculty member. In 1987 he joined the faculty at Albert Einstein College of Medicine as professor and chair of the biochemistry department. [4]
Earl Wilbur Sutherland Jr. was an American pharmacologist and biochemist born in Burlingame, Kansas. Sutherland won a Nobel Prize in Physiology or Medicine in 1971 "for his discoveries concerning the mechanisms of the action of hormones", especially epinephrine, via second messengers, namely cyclic adenosine monophosphate, or cyclic AMP.
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