State Route 114 is a primary state highway in the U.S. state of Virginia. Known as Peppers Ferry Road, the state highway runs 10.32 miles (16.61 km) from U.S. Route 11 in Fairlawn east to US 460 in Christiansburg. SR 114 is the northernmost of three east–west highways between Radford and Christiansburg and the most direct highway between Radford and Blacksburg. The state highway also connects those cities with the Radford Army Ammunition Plant.
State Route 70 is a primary state highway in Lee County, Virginia, running from the Tennessee state line to U.S. Route 58 in Jonesville. Its continuation in Tennessee, also numbered State Route 70, continues south to the North Carolina state line at North Carolina Highway 208.
State Route 71 is a primary state highway in the southwest part of the U.S. state of Virginia. It runs from Gate City northeast to Lebanon, mostly through river valleys. Despite running more east–west than north–south, it is signed north–south; it parallels the similarly-oriented U.S. Route 11 and Interstate 81.
State Route 72 is a primary state highway in the southwest part of the U.S. state of Virginia. It runs from SR 71 in Gate City north to SR 65 at Fort Blackmore, northeast with SR 65 to Dungannon, and north via Coeburn to SR 83 near Clintwood.
State Route 75 is a primary state highway in the southwest part of the U.S. state of Virginia, running southwest from U.S. Route 11 and U.S. Route 58 Alternate in Abingdon to Tennessee's State Route 44.
U.S. Route 460 (US 460) in Virginia runs west-east through the southern part of the Commonwealth. The road has two separate pieces in Virginia, joined by a relatively short section in West Virginia. Most of US 460 is a four-lane divided highway and is a major artery in the southern third of the state. From Petersburg to Suffolk, US 460 is a four-lane non-divided highway. It is a popular alternative to Interstate 64 (I-64) when going from Richmond and other points in central Virginia to the Currituck Sound and Outer Banks of North Carolina, avoiding the congestion and tunnels of the more northerly I-64 corridor. The road passes through several small towns that built up at stops along the railroad line. Two of these, Windsor and Waverly, have earned reputations for being speed traps.
State Route 16 is a primary state highway in the southwest part of the U.S. state of Virginia. It runs from the North Carolina border at North Carolina Highway 16 north to the West Virginia border at West Virginia Route 16, passing through the towns of Troutdale, Marion, and Tazewell. Highway 16 is part of a three-state route 16 that connects the Charlotte region with northwestern West Virginia.
State Route 80 is a primary state highway in the southwest part of the U.S. state of Virginia. It runs from the Kentucky state line at Breaks Interstate Park east to U.S. Route 11 near Meadowview. Kentucky Route 80 and Missouri's Route 80 continue the number west to Matthews, Missouri.
U.S. Route 19 is a part of the U.S. Highway System that runs from Memphis, Florida to Erie, Pennsylvania. In Virginia, the highway runs 88.89 miles (143.05 km) between two pairs of twin cities: Bristol, Tennessee and Bristol, Virginia, at the Virginia–Tennessee state line, and Bluefield, Virginia and Bluefield, West Virginia, at the Virginia–West Virginia state line. Between its endpoints, US 19 has lengthy concurrencies with US 11, US 58 Alternate, and US 460 during its course connecting Abingdon, Lebanon, and Tazewell within Washington, Russell, and Tazewell counties in Southwest Virginia.
State Route 13 is a primary state highway in the U.S. state of Virginia. Known as Old Buckingham Road, the state highway runs 24.08 miles (38.75 km) from U.S. Route 60 and SR 45 in Cumberland east to US 60 in Plain View. SR 13 parallels US 60 to the south through eastern Cumberland County and western Powhatan County and passes through the latter county's seat of Powhatan. The state highway is the only state-numbered highway in Virginia that shares a number with a U.S. Highway but does not form a state-numbered extension of that U.S. Highway. SR 13's number comes from being a segment of the original cross-state SR 13 in 1918; that highway included portions of modern US 60. In 1933, US 60 was shifted to its present corridor between Buena Vista and Richmond, replacing SR 13. Two years later, SR 13 was assigned to Old Buckingham Road when US 60 was moved to its present alignment from Cumberland to east of Powhatan.
State Route 8 is a primary state highway in the U.S. state of Virginia. The state highway runs 55.88 miles (89.93 km) from the North Carolina state line near Palmetto, where the highway continues south as North Carolina Highway 8, north to U.S. Route 11 in Christiansburg. SR 8 is part of a 151-mile (243 km) two-state highway 8 system and is the main north–south highway of Patrick County, Floyd County, and southern Montgomery County, connecting their respective county seats of Stuart, Floyd, and Christiansburg with each other and with the Blue Ridge Parkway. The state highway also links the New River Valley region of Virginia with Southside Virginia via US 58 and the Piedmont Triad of North Carolina via NC 8.
In the US state of Virginia, some state highways have been specifically designated to serve state parks and state institutions. State Route 217 and the range of numbers from State Route 302 to State Route 399 are currently used (non-exclusively) for this purpose. For a list of very short Virginia primary state highways, see List of primary state highways in Virginia shorter than one mile.
Virginia Byway 
SR 80 near Honaker 
US 460 in Richlands 
SR 616 at Jewell Ridge 
