WDR46

WDR46
Identifiers
Aliases	WDR46 , BING4, C6orf11, FP221, UTP7, WD repeat domain 46
External IDs	OMIM: 611440; MGI: 1931871; HomoloGene: 3981; GeneCards: WDR46; OMA:WDR46 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p21.32 Start 33,279,108 bp [1] End 33,289,247 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 B1 Start 34,159,634 bp [2] End 34,168,671 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte stromal cell of endometrium anterior pituitary mucosa of transverse colon spleen appendix left testis skin of leg apex of heart right lobe of thyroid gland Top expressed in Gonadal ridge epiblast submandibular gland gastrula abdominal wall hair follicle mandibular prominence Paneth cell primitive streak maxillary prominence More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding Cellular component small-subunit processome nucleolus 90S preribosome nucleus nucleoplasm cellular component Biological process maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) positive regulation of protein targeting to mitochondrion rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9277 57315 Ensembl ENSG00000206284 ENSG00000236222 ENSG00000204221 ENSG00000226916 ENSG00000227057 n/a ENSMUSG00000024312 UniProt O15213 Q9Z0H1 RefSeq (mRNA) NM_001164267 NM_005452 NM_020603 RefSeq (protein) NP_001157739 NP_005443 NP_065628 Location (UCSC) Chr 6: 33.28 – 33.29 Mb Chr 17: 34.16 – 34.17 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

WD repeat-containing protein 46 is a protein that in humans is encoded by the WDR46 gene. ^{[5] [6] [7]}

References

1. ENSG00000236222, ENSG00000204221, ENSG00000226916, ENSG00000227057 GRCh38: Ensembl release 89: ENSG00000206284, ENSG00000236222, ENSG00000204221, ENSG00000226916, ENSG00000227057 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000024312 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Herberg JA, Beck S, Trowsdale J (May 1998). "TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC". J Mol Biol. 277 (4): 839–57. doi:10.1006/jmbi.1998.1637. PMID   9545376.
6. Herberg JA, Sgouros J, Jones T, Copeman J, Humphray SJ, Sheer D, Cresswell P, Beck S, Trowsdale J (Mar 1998). "Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC". Eur J Immunol. 28 (2): 459–67. doi:10.1002/(SICI)1521-4141(199802)28:02<459::AID-IMMU459>3.0.CO;2-Z. PMID   9521053. S2CID   35772444.
7. "Entrez Gene: WDR46 WD repeat domain 46".

Further reading

• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi: 10.1073/pnas.0404089101 . PMC   524842 . PMID   15498874.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC   1459365 . PMID   16565220.