ZNF23

ZNF23
Identifiers
Aliases	ZNF23 , KOX16, ZNF359, ZNF612, Zfp612, zinc finger protein 23
External IDs	OMIM: 194527; MGI: 2443465; HomoloGene: 27083; GeneCards: ZNF23; OMA:ZNF23 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16q22.2 Start 71,447,597 bp [1] End 71,463,095 bp [1]
Gene location (Mouse) Chr. Chromosome 8 (mouse) [2] Band 8|8 D3 Start 110,806,378 bp [2] End 110,819,373 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad Pituitary Gland anterior pituitary right uterine tube ganglionic eminence cerebellar hemisphere sural nerve testicle right hemisphere of cerebellum Hypothalamus Top expressed in pontine nuclei Rostral migratory stream ventral tegmental area medial vestibular nucleus paraventricular nucleus of hypothalamus lateral hypothalamus substantia nigra dorsal tegmental nucleus dorsomedial hypothalamic nucleus arcuate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding metal ion binding nucleic acid binding protein binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7571 234725 Ensembl ENSG00000167377 ENSMUSG00000044676 UniProt P17027 n/a RefSeq (mRNA) NM_145911 NM_001304492 NM_001304493 NM_001304494 NM_175480 RefSeq (protein) NP_001291421 NP_001291422 NP_001291423 NP_666016 NP_001368894 NP_001368895 NP_001368896 NP_001368897 NP_001368898 NP_001368899 NP_001368900 NP_001368901 NP_001368902 NP_001368903 NP_001368904 NP_001368905 NP_001368906 NP_001368907 NP_001368908 NP_001368909 NP_001368910 NP_001368913 n/a Location (UCSC) Chr 16: 71.45 – 71.46 Mb Chr 8: 110.81 – 110.82 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 23 is a protein that in humans is encoded by the ZNF23 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000167377 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000044676 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: ZNF23 zinc finger protein 23 (KOX 16)".

Further reading

• Huang C, Jia Y, Yang S, et al. (2007). "Characterization of ZNF23, a KRAB-containing protein that is downregulated in human cancers and inhibits cell cycle progression". Exp. Cell Res. 313 (2): 254–63. doi:10.1016/j.yexcr.2006.10.009. PMID   17137575.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Zhou L, Zhu C, Luo K, et al. (2002). "Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development". Biochem. Biophys. Res. Commun. 295 (4): 862–8. doi:10.1016/S0006-291X(02)00759-3. PMID   12127974.
• Cannizzaro LA, Aronson MM, Thiesen HJ (1993). "Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24". Hum. Genet. 91 (4): 383–5. doi:10.1007/BF00217362. PMID   8500793. S2CID   26273171.
• Abrink M, Aveskogh M, Hellman L (1995). "Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937". DNA Cell Biol. 14 (2): 125–36. doi:10.1089/dna.1995.14.125. PMID   7865130.
• Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID   2288909.