ZNF473

ZNF473
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2EMB, 2EMC, 2EME, 2EOU, 2EOX, 2EOY, 2EOZ, 2YRH, 2YRJ, 2YSV, 2YTD, 2YTE, 2YTT, 2YU5
Identifiers
Aliases	ZNF473 , HZFP100, ZN473, zinc finger protein 473, ZFP100
External IDs	OMIM: 617908; MGI: 2442697; HomoloGene: 18698; GeneCards: ZNF473; OMA:ZNF473 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19q13.33 Start 50,025,714 bp [1] End 50,053,414 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 B3 Start 44,380,904 bp [2] End 44,400,474 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube testicle right testis left testis gonad olfactory zone of nasal mucosa sperm anterior pituitary ventricular zone islet of Langerhans Top expressed in primary oocyte secondary oocyte zygote urethra otic vesicle male urethra tail of embryo spermatocyte epiblast primitive streak More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding DNA binding nucleic acid binding protein binding Cellular component Cajal body nucleus intracellular anatomical structure nucleoplasm Biological process termination of RNA polymerase II transcription mRNA 3'-end processing by stem-loop binding and cleavage regulation of transcription, DNA-templated histone mRNA metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25888 243963 Ensembl ENSG00000142528 ENSMUSG00000048012 UniProt Q8WTR7 Q8BI67 RefSeq (mRNA) NM_001006656 NM_001308424 NM_015428 NM_001289836 NM_001289837 NM_001289838 NM_001289839 NM_178734 RefSeq (protein) NP_001006657 NP_001295353 NP_056243 NP_001276765 NP_001276766 NP_001276767 NP_001276768 NP_848849 Location (UCSC) Chr 19: 50.03 – 50.05 Mb Chr 7: 44.38 – 44.4 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 473 is a protein that in humans is encoded by the ZNF473 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000142528 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000048012 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Dominski Z, Erkmann JA, Yang X, Sanchez R, Marzluff WF (Jan 2002). "A novel zinc finger protein is associated with U7 snRNP and interacts with the stem-loop binding protein in the histone pre-mRNP to stimulate 3'-end processing". Genes Dev. 16 (1): 58–71. doi:10.1101/gad.932302. PMC   155312 . PMID   11782445.
6. "Entrez Gene: ZNF473 zinc finger protein 473".

Further reading

• Wagner EJ, Marzluff WF (2006). "ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase". Mol. Cell. Biol. 26 (17): 6702–12. doi:10.1128/MCB.00391-06. PMC   1592837 . PMID   16914750.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Pillai RS, Grimmler M, Meister G, et al. (2003). "Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing". Genes Dev. 17 (18): 2321–33. doi:10.1101/gad.274403. PMC   196468 . PMID   12975319.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Hirosawa M, Nagase T, Ishikawa K, et al. (2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi: 10.1093/dnares/6.5.329 . PMID   10574461.