ZNF76

ZNF76
Identifiers
Aliases	ZNF76 , D6S229E, ZNF523, Zfp523, zinc finger protein 76
External IDs	OMIM: 194549; MGI: 2687278; HomoloGene: 2569; GeneCards: ZNF76; OMA:ZNF76 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p21.31 Start 35,258,909 bp [1] End 35,295,985 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 A3.3 Start 28,396,103 bp [2] End 28,424,860 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland anterior pituitary apex of heart right adrenal cortex left ovary right uterine tube right ovary left adrenal cortex right hemisphere of cerebellum Top expressed in interventricular septum superior frontal gyrus genital tubercle neural layer of retina primary visual cortex tail of embryo dentate gyrus of hippocampal formation granule cell ventricular zone Rostral migratory stream olfactory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding DNA binding nucleic acid binding DNA-binding transcription activator activity, RNA polymerase II-specific sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription, DNA-templated regulation of transcription by RNA polymerase III transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7629 224656 Ensembl ENSG00000065029 ENSMUSG00000024220 UniProt P36508 Q8BMU0 RefSeq (mRNA) NM_001292032 NM_003427 NM_172617 NM_001357995 RefSeq (protein) NP_001278961 NP_003418 NP_766205 NP_001344924 Location (UCSC) Chr 6: 35.26 – 35.3 Mb Chr 17: 28.4 – 28.42 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 76 is a protein that in humans is encoded by the ZNF76 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000065029 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000024220 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ragoussis J, Senger G, Mockridge I, Sanseau P, Ruddy S, Dudley K, Sheer D, Trowsdale J (Dec 1992). "A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11". Genomics. 14 (3): 673–9. doi:10.1016/S0888-7543(05)80167-3. PMID   1427894.
6. "Entrez Gene: ZNF76 zinc finger protein 76 (expressed in testis)".

Further reading

• Prigge JR, Schmidt EE (2006). "Interaction of Protein Inhibitor of Activated STAT (PIAS) Proteins with the TATA-binding Protein, TBP". J. Biol. Chem. 281 (18): 12260–9. doi: 10.1074/jbc.M510835200 . PMC   2030495 . PMID   16522640.
• Zheng G, Yang YC (2006). "Acetylation and alternative splicing regulate ZNF76-mediated transcription". Biochem. Biophys. Res. Commun. 339 (4): 1069–75. doi:10.1016/j.bbrc.2005.11.122. PMID   16337145.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Zheng G, Yang YC (2004). "ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation". J. Biol. Chem. 279 (41): 42410–21. doi: 10.1074/jbc.M407287200 . PMID   15280358.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC   442148 . PMID   15231748.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Myslinski E, Krol A, Carbon P (1998). "ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf". J. Biol. Chem. 273 (34): 21998–2006. doi: 10.1074/jbc.273.34.21998 . PMID   9705341.