ZNF76

ZNF76
Identifiers
Aliases	ZNF76 , D6S229E, ZNF523, Zfp523, zinc finger protein 76
External IDs	OMIM: 194549 MGI: 2687278 HomoloGene: 2569 GeneCards: ZNF76
Gene location (Human)
Chr.	Chromosome 6 (human)
End	35,295,985 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	28,424,860 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; anterior pituitary; ; right uterine tube; ; gastric mucosa; ; canal of the cervix; ; minor salivary gland; ; spleen; ; left uterine tube; ; body of stomach;
	Top expressed in
	interventricular septum; ; superior frontal gyrus; ; olfactory epithelium; ; retinal pigment epithelium; ; cerebellar cortex; ; hand; ; mirror; ; otolith organ; ; olfactory tubercle; ; prefrontal cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding ; DNA binding ; nucleic acid binding ; DNA-binding transcription activator activity, RNA polymerase II-specific ; sequence-specific DNA binding ; DNA-binding transcription factor activity, RNA polymerase II-specific ;
Cellular component	nucleus ;
Biological process	regulation of transcription, DNA-templated ; regulation of transcription by RNA polymerase II ; transcription, DNA-templated ; regulation of transcription by RNA polymerase III ; transcription by RNA polymerase II ; positive regulation of transcription by RNA polymerase II ;
	Sources:Amigo / QuickGO
Orthologs
	7629
	224656
	ENSG00000065029
	ENSMUSG00000024220
	P36508
	Q8BMU0
	NM_001292032 ; NM_003427
	NM_172617 ; NM_001357995
	NP_001278961 ; NP_003418
	NP_766205 ; NP_001344924
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 14, 2022

Zinc finger protein 76 is a protein that in humans is encoded by the ZNF76 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000065029 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024220 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Ragoussis J, Senger G, Mockridge I, Sanseau P, Ruddy S, Dudley K, Sheer D, Trowsdale J (Dec 1992). "A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11". Genomics. 14 (3): 673–9. doi:10.1016/S0888-7543(05)80167-3. PMID 1427894.
↑ "Entrez Gene: ZNF76 zinc finger protein 76 (expressed in testis)".

Prigge JR, Schmidt EE (2006). "Interaction of Protein Inhibitor of Activated STAT (PIAS) Proteins with the TATA-binding Protein, TBP". J. Biol. Chem. 281 (18): 12260–9. doi: 10.1074/jbc.M510835200 . PMC 2030495 . PMID 16522640.
Zheng G, Yang YC (2006). "Acetylation and alternative splicing regulate ZNF76-mediated transcription". Biochem. Biophys. Res. Commun. 339 (4): 1069–75. doi:10.1016/j.bbrc.2005.11.122. PMID 16337145.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Zheng G, Yang YC (2004). "ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation". J. Biol. Chem. 279 (41): 42410–21. doi: 10.1074/jbc.M407287200 . PMID 15280358.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148 . PMID 15231748.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Myslinski E, Krol A, Carbon P (1998). "ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf". J. Biol. Chem. 273 (34): 21998–2006. doi: 10.1074/jbc.273.34.21998 . PMID 9705341.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000065029 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024220 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1427894-5] Ragoussis J, Senger G, Mockridge I, Sanseau P, Ruddy S, Dudley K, Sheer D, Trowsdale J (Dec 1992). "A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11". Genomics. 14 (3): 673–9. doi:10.1016/S0888-7543(05)80167-3. PMID 1427894.

[entrez-6] "Entrez Gene: ZNF76 zinc finger protein 76 (expressed in testis)".

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ZNF76

Related Research Articles

References

Further reading