ZNF8

ZNF8
Identifiers
Aliases	ZNF8 , HF.18, Zfp128, zinc finger protein 8
External IDs	OMIM: 194532 MGI: 2389445 HomoloGene: 10889 GeneCards: ZNF8
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19q13.43 Start 58,278,955 bp [1] End 58,302,791 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 A1 Start 12,615,104 bp [2] End 12,627,349 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence caput epididymis corpus epididymis stromal cell of endometrium retinal pigment epithelium tibia Brodmann area 23 middle temporal gyrus germinal epithelium bronchial epithelial cell Top expressed in otolith organ hand utricle spermatocyte seminiferous tubule renal corpuscle medial ganglionic eminence substantia nigra foot trigeminal ganglion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding zinc ion binding metal ion binding nucleic acid binding Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II BMP signaling pathway transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7554 243833 Ensembl ENSG00000278129 ENSMUSG00000060397 UniProt P17098 Q8BGV5 RefSeq (mRNA) NM_021089 NM_153802 RefSeq (protein) NP_066575 NP_722497 Location (UCSC) Chr 19: 58.28 – 58.3 Mb Chr 7: 12.62 – 12.63 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 8 is a protein that in humans is encoded by the ZNF8 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000278129 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000060397 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lania L, Donti E, Pannuti A, Pascucci A, Pengue G, Feliciello I, La Mantia G, Lanfrancone L, Pelicci PG (Apr 1990). "cDNA isolation, expression analysis, and chromosomal localization of two human zinc finger genes". Genomics. 6 (2): 333–40. doi:10.1016/0888-7543(90)90574-E. PMID   2106481.
6. "Entrez Gene: ZNF8 zinc finger protein 8".

Further reading

• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID   16964243. S2CID   14294292.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Jiao K, Zhou Y, Hogan BL (2002). "Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1". Mol. Cell. Biol. 22 (21): 7633–44. doi:10.1128/MCB.22.21.7633-7644.2002. PMC   135661 . PMID   12370310.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.